Results 151 to 160 of about 2,923,921 (341)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

R&D Stages and Stock Price Reactions in the Japanese Market

, 2009
Shohei Nagayama, Fumiko Takeda
openalex   +1 more source

Vintners call for minimum unit pricing on off-licence sales 'to curb house party outbreaks'. [PDF]

, 2020
Gareth MacNamee
openalex  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Competencia y precios en el mercado farmacéutico mexicano Competition and prices in the Mexican pharmaceutical market

Salud Pública de México, 2008
Las formas que asume la competencia en el mercado definen el nivel de precios. El mercado farmacéutico contiene submercados con diferente grado de competencia; por un lado existen productos innovadores con patente y, por el otro, genéricos con marca ...
Raúl E Molina-Salazar, Eloy González-Marín, Carolina Carbajal-de Nova   +2 more
doaj  

An Econometric Study for Analyzing and Forecasting Consumer Prices of Selected Fresh Vegetables دراسة إقتصادية قياسية للتنبؤ بأسعار المستهلک لبعض منتجات الخضر الطازجة [PDF]

, 2021
محمود عرفة, حازم رفعت
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Asymmetric price effects of competition [PDF]

This paper examines how the distribution of prices changes with the number of competitors in the market. Using gasoline price data from the Netherlands we find that as competition increases, the distribution of prices spreads out: the low prices go down ...
Lach, Saul, Moraga, Jose L.
core  

The Effects of Quantitative Easing on House Prices: USA vs. EU

, 2015
Majda Glotic
openalex   +1 more source

4. 'Excellence and Equity': Merit as the Price of Admission [PDF]

, 2021
Sophie Spieler
openalex   +1 more source