Results 161 to 170 of about 410,230 (271)

Systematic Metabolic Engineering and Model‐Guided Optimization for High‐Level Production of L‐Theanine from Xylose in Escherichia coli

Advanced Science, EarlyView.
This study is pioneering in constructing the shortest known synthetic pathway for L‐theanine production from xylose within E coli. Through comprehensive metabolic engineering strategies, our engineered strain achieved the highest reported L‐theanine titer from xylose, with a titer of 95.42 g/L, and a yield of 0.55 g/g.
Haolin Han, Boyuan Xue, Guangqi Shan, Meng Meng, Shaojie Wang, Haijia Su   +5 more
wiley   +1 more source

Multi-channel pricing strategies for pharmaceutical supply chains considering channel power and price competition. [PDF]

PLoS One
Wen Y, Wei Y, Yu X.
europepmc   +1 more source

Bridging Green Chemistry and Circular Economy: A Pathway to Sustainable Polyester Plastics Through Feedstock, Synthesis, and Waste Upcycling

Advanced Science, EarlyView.
This review summarizes green and low‐carbon strategies throughout the entire life cycle of polyester plastics, including sustainable monomer synthesis, optimization polymerization, efficient recycling, and advanced upcycling technologies. The synergistic implementation of these strategies is expected to significantly promote the development of a ...
Jinzhou Li, Junliang Chen, Yingbing Zhang, Li Wang, Pin Gao, Jianping Yang   +5 more
wiley   +1 more source

Are Turkish pharmaceutical pricing strategies an access barrier to oncology medicines for Türkiye? [PDF]

Front Pharmacol
Vural EH, Kaskati T, Vural İM, Özalp MA, Gümüşel B.   +4 more
europepmc   +1 more source

Pricing Strategies in Dual-Channel Reverse Supply Chains Considering Fairness Concern. [PDF]

Int J Environ Res Public Health, 2019
Wu D, Chen J, Yan R, Zhang R.
europepmc   +1 more source

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

Advanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke, Tania Kamal, Taylor E. Divita, Artem N. Pachikov, Chad A. LaGrange, Rajesh Ravichandran, Martha Morton, Robert Powers, Haowen Qiu, Jean‐Jack M. Riethoven, Colm Morrissey, Melinda Wojtkiewicz, Rebekah L. Gundry, Carol A. Casey, Armen Petrosyan   +14 more
wiley   +1 more source

Congressional Investigation of RevAssist-Linked and General Pricing Strategies for Lenalidomide. [PDF]

JCO Oncol Pract
Bennett CL, Gibbons JB, Trujillo A, Carson KR, Knopf K, Nabhan C, Rosen ST, Aboulafia DM.   +7 more
europepmc   +1 more source

Fair but Risky? Recycle Pricing Strategies in Closed-Loop Supply Chains. [PDF]

Int J Environ Res Public Health, 2018
He J, Zhang L, Fu X, Tsai FS.
europepmc   +1 more source

How AI Shapes the Future Landscape of Sustainable Building Design With Climate Change Challenges?

Advanced Science, EarlyView.
This review examines how artificial intelligence reshapes sustainable building design faced with climate change challenges. The authors synthesize existing studies to demonstrate AI's transformative potential across design lifecycle phases from climate‐aware form generation to performance optimization.
Pengyuan Shen, Xiaoni Gao, Shuai Lu, Yi Zhang, Xing Zheng, Matthaios Santamouris   +5 more
wiley   +1 more source

Relationship between pharmaceutical pricing strategies with price, availability, and affordability of cardiovascular disease medicines: surveys in Qatar and Lebanon. [PDF]

BMC Health Serv Res, 2019
Abdel Rida N, Mohamed Ibrahim MI, Babar ZUD.   +2 more
europepmc   +1 more source