Results 191 to 200 of about 1,887 (235)

Spines and Prickles

, 2018
Dennis Wm. Stevenson
core   +1 more source

Trafficking Deficiency of TMEM175 Variants in Parkinson's Disease Pathogenesis and the Prospects of Precision Medicine

Advanced Science, EarlyView.
This study identifies that the PD‐associated TMEM175‐L156P variant disrupts lysosomal ion channel trafficking by causing aberrant endoplasmic reticulum retention. A “chaperone–agonist” bifunctional small molecule restores TMEM175‐L156P lysosomal localization and channel function, thereby alleviating PD‐relevant cellular phenotypes and highlighting a ...
Ting Luo, Yu He, Shuyao Li, Haoyu Guan, Ruili Cui, Yu Shi, Zhongwen Jiang, Siyu Wang, Xuan Li, Jiyuan Li, Mei Hu, Yupeng Zhou, Beisha Tang, Yanyan Zhang, Zhaobing Gao, Yu Zhou, Zhenhua Liu, Ping Li   +17 more
wiley   +1 more source

Genome and transcriptomics provide insights on stipular spine morphogenesis in <i>Robinia pseudoacacia</i>. [PDF]

For Res (Fayettev)
Tian Y, Zhao Y, Sun Y, Bo W, Huang X, Wen J, Wang S, Jing Y, Zhao Y, Shi T, El-Kassaby YA, Zhang B, Zhang Y, Yang H, Peng Z, Han J, Li Y, Li Q.   +17 more
europepmc   +1 more source

A Rigid–Foldable Kirigami‐Inspired Metamorphic Mechanism With Programmable Motion Modes and Self‐Locking

Advanced Science, EarlyView.
Geometric constraint reconfiguration enables a rigid–foldable kirigami‐inspired mechanism to switch between twisting, directional translation, and self‐locking states. By encoding multifunctionality directly into its architecture, the mechanism achieves multimodal motion and passive locking without reassembly, providing a compact platform for adaptive ...
Jianlin Wang, Zhongmin Song, Ketao Zhang
wiley   +1 more source

Advanced Botanical Research in the Mediterranean Area: Studies in Honor of Prof. Francesco Maria Raimondo on the Occasion of His 80th Birthday. [PDF]

Plants (Basel)
Venturella G, Domina G.
europepmc   +1 more source

Unveiling Mechanisms of SEI Formation and Sodium Loss in Sodium Batteries via Interface Reactor Sampling

Advanced Science, EarlyView.
An “Interface Reactor” strategy boosts simulation stability by 2–3 orders of magnitude, enabling stable 100 ns molecular dynamics of electrode‐electrolyte interfaces. Distinct SEI formation mechanisms are revealed: mixed co‐formation in carbonates versus surface‐energy‐controlled NaF crystallization in ethers. Metadynamics simulations further elucidate
Zhoulin Liu, Ziliang Wang, Zherui Chen, Jianchun Sha, Fengzijun Pan, Pingyang Zhang, Yinghe Zhang   +6 more
wiley   +1 more source

The control of prickle formation in Rubus

St. Aubin B, Poorten T, Fister A, Ochsenfeld C, Reiner J, Castillo AS, Aryal R, Brůna T, Dudchenko O, Sargent DJ, Mead D, Buti M, Silva A, Pham M, Weisz D, Bassil N, Ashrafi H, Aiden EL, Graham N, Chauhan D, Dean E, Lowry W, Redpath L, Marri P, Lawit S, Pham G, Worthington M, Crawford BC.   +27 more
europepmc   +1 more source

Comparative Phytochemical and Antiviral Characteristics of <i>Dipsacus asperoides</i> and <i>Phlomis umbrosa</i> Against Influenza A Virus: LC-QTOF-MS Profiling and Exploratory Network Pharmacology. [PDF]

Plants (Basel)
Park JS, Ryu SM, Lee J, Yang S, Kim HS, Seo YH, Lee HJ, Park I, Jeong S, Jung J, Park SJ, Kim JS.   +11 more
europepmc   +1 more source

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

Advanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen, Shilin Zhang, Xiaojie Deng, Wenqiang Xie, Fen Xu, Jie Shen, Hua Liang   +6 more
wiley   +1 more source

PE (Prickly Eggplant) encoding a cytokinin-activating enzyme responsible for the formation of prickles in eggplant. [PDF]

Hortic Res
Zhang L, Zhang R, Yan P, Zeng L, Zhao W, Feng H, Mu R, Hou W.   +7 more
europepmc   +1 more source