Results 21 to 30 of about 170,294 (297)

Adolescent engagement in a stepped care, transdiagnostic mental health intervention delivered in Indian schools

open access: yesDiscover Psychology
Given the relationship between poor engagement and worse treatment outcomes, improving engagement has been the focus of attention in recent years. Engagement is a particular challenge among minoritized and otherwise challenged youth, such as those from ...
Resham Gellatly   +13 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Pride in Teachers’ Everyday Work. Conditions and Contexts

open access: yesQualitative Sociology Review, 2020
The aim of this article is to elaborate on the reasons behind feeling the emotion of pride within the professional context of actions undertaken by contemporary Polish teachers.
Beata Pawłowska
doaj   +1 more source

Present and future of proteomics data curation at the PRIDE database [PDF]

open access: yes, 2009
Significant progress has been made in improving the accessibility and utility of the large amounts of generated high-throughput proteomics data by the introduction of publicly available proteomics repositories.
Juan Antonio Vizcaino   +2 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Establishment of an Inferred Reference Range for Blood Ammonia in Dogs and Cats Using a Point-of-Care Assay

open access: yesVeterinary Sciences
Point-of-care (POC) tests for blood ammonia (BA) measurement have not been well evaluated in veterinary species. This cross-sectional study sought to establish an inferred reference interval for BA using a POC analyser in dogs and cats. Blood ammonia was
Giulia Specchia   +2 more
doaj   +1 more source

Davis County Utah Pride 2023 Connell O\u27Donovan Speaking [3]

open access: yes, 2023
Color photograph of Connell O\u27Donovan Speaking at the 2023 Davis County Pride ...
Tracy Johnson Faulkner
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Case Report: Filum terminale extradural arachnoid diverticulum associated with tethered cord syndrome in a French Bulldog

open access: yesFrontiers in Veterinary Science
Extradural arachnoid diverticula and tethered cord syndrome are rare disorders in dogs, and their simultaneous occurrence with a possible mechanistic association has not been previously reported.
Anna Davis   +6 more
doaj   +1 more source

Davis County Utah Pride 2023 Connell O\u27Donovan, Madazon CanCan

open access: yes, 2023
Color photograph of Connell O\u27Donovan and Madazon Can Can on stage at the 2023 Davis County Pride ...
Unknown
core  

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