Results 61 to 70 of about 55,734 (257)

Pastores, ovelhas desgarradas e as disputas pelo rebanho: Sobre a transcrucificação na Parada do orgulho LGBT de São Paulo em 2015

Revista Crítica de Ciências Sociais, 2016
The LGBT Pride Parade in São Paulo (Brazil) is one of biggest of its kind in the world. Its 19th edition, which took place in July 2015, was marked by two events that received extensive media coverage: a crucified transgender woman denouncing gender ...
Rodrigo Otávio Moretti-Pires, Zeno Carlos Tesser Júnior, Marcelo Vieira, Murilo dos Santos Moscheta   +3 more
doaj   +1 more source

MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes

Advanced Science, EarlyView.
A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak, Juliane Tschuck, Stefanie A. I. Weiß, Daniel Kaemena, Karolin Klimm, Ana Galhoz, Larissa Ringelstetter, Myles Fennell, Juliane Merl‐Pham, Anna Artati, Stefanie Strasser, Ralph Garippa, Michael Witting, Hans Zischka, Joel A. Schick, Stefanie M. Hauck, Michael P. Menden, Michelle Vincendeau, Brent R. Stockwell, Kamyar Hadian   +19 more
wiley   +1 more source

A multiple regression analysis of self-compassion, authentic pride, and self-reported prestige

Current Research in Behavioral Sciences
Self-compassion (SC) refers to an adaptive way of relating to one’s experiences during times of failure or distress and is theorized to encourage viewing relationships as sources of connection rather than as tools to enhance self-esteem.
Joacim Forell, Jonatan Näsström, Joakim Norberg   +2 more
doaj   +1 more source

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao, Lin Zhang, Gufang Shen, Yangfan Lv, Tianshu Fang, Ya Cao, Qiongyi Zhang, Feng Xu, Chungang Liu   +8 more
wiley   +1 more source

Thoughts on Pride: No Coal Dug

Open Library of Humanities, 2019
Pride tells the story of a group of London lesbian and gay activists who offer their support to the striking miners in Dulais, South Wales. This article reflexively uncovers the layers through which the story of LGSM has been remembered, forgotten, and ...
Lucy Robinson
doaj   +2 more sources

PhosSight: A Unified Deep Learning Framework Boosting and Accelerating Phosphoproteome Identification to Enable Biological Discoveries

Advanced Science, EarlyView.
PhosSight is a unified deep‐learning framework for phosphoproteome identification, featured by a phosphorylation‐aware detectability predictor. It improves identification sensitivity in DDA through deep re‐localization and rescoring, accelerates DIA searches by detectability‐guided spectral library pruning, and expands phosphoproteome coverage to ...
Ben Wang, Zhiyuan Cheng, Chengying She, Hongwei Zhao, Jiahui Zhang, Lin Lv, Zhihao Yan, Hongwen Zhu, Lizhuang Liu, Yan Fu, Xinpei Yi   +10 more
wiley   +1 more source

National pride and tax compliance: A laboratory experiment using a physiological marker

PLoS ONE, 2023
This paper reports on a laboratory experiment designed specifically to test the influence of national pride on tax honesty while using a physiological marker to observe emotional responses to patriotic priming.
Alison Macintyre, Ho Fai Chan, Markus Schaffner, Benno Torgler   +3 more
doaj  

‘What I was told about lesbians really did shock me. It can’t be true, can it? You’re all vegetarians?’: Greywashing Gay Shame in Pride

Open Library of Humanities, 2020
Celebrated by film journalists as the feel-good film of 2014 (Kermode, 2014; Osboldstone, 2014), Pride depicted the unlikely alliance between a group of London based gay activists and the miners from a small, Welsh village during the miners’ strike of ...
Niall Richardson
doaj   +2 more sources

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

Advanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li, Muyang Li, Lei Sun, Ying Yang, Yuanshun Wu, Ziyi Yin, Anni Wang, Peiyang Zhou, Shaoxiang Luo, Jian Chen, Jun Qin, Zhibing Ai, Zilong Yuan, Zhiqiang Dong, Min Zhang   +14 more
wiley   +1 more source

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

Advanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A. Chan, William C Merrick, Zheng‐Rong Lu, Boaz Tirosh   +6 more
wiley   +1 more source