Results 101 to 110 of about 5,015,001 (272)

Single‐Cell Morphomechanics of Prostate Cancer‐Associated Fibroblasts Identifies Distinct Features Associated with Patient Outcome

open access: yesAdvanced Science, EarlyView.
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside   +11 more
wiley   +1 more source

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

open access: yesAdvanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen   +7 more
wiley   +1 more source

Triboelectric Tactile Transducers for Neuromorphic Sensing and Synaptic Emulation: Materials, Architectures, and Interfaces

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
Triboelectric nanogenerators are vital for sustainable energy in future technologies such as wearables, implants, AI, ML, sensors and medical systems. This review highlights improved TENG neuromorphic devices with higher energy output, better stability, reduced power demands, scalable designs and lower costs.
Ruthran Rameshkumar   +2 more
wiley   +1 more source

Economic and Environmental Tradeoffs in Cultivating Short Food Supply Chains With Urban Indoor Agriculture

open access: yesAgribusiness, EarlyView.
ABSTRACT This study advances the literature on sustainable urban agriculture and alternative sustainable food production systems, which have gained momentum due to the need to strengthen regional food supply chains and meet the growing urban demand for fresh food. Indoor agriculture (IA) holds promise for year‐round cultivation of fresh produce even in
Joseph Seong   +2 more
wiley   +1 more source

Bridging High‐Fidelity Simulations and Physics‐Based Learning using a Surrogate Model for Soft Robot Control

open access: yesAdvanced Intelligent Systems, EarlyView.
A surrogate‐model‐based framework is proposed for combining high‐fidelity finite element method and efficient physics simulations to enable fast, accurate soft robot simulation for reinforcement learning, validated through sim‐to‐real experiments. Soft robotics holds immense promise for applications requiring adaptability and compliant interactions ...
Taehwa Hong   +3 more
wiley   +1 more source

Current‐Limiting Control Strategies in Variable Capacitance Electrostatic Energy Harvesters

open access: yesAdvanced Intelligent Systems, EarlyView.
This work introduces control strategies for electrostatic energy harvesters that balance energy yield with current limitations. Two approaches are explored: traditional peak‐triggered controls, and newly developed quadrature controls, which use smooth voltage profiles.
Alireza Jalaliankhakshour   +4 more
wiley   +1 more source

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