Results 141 to 150 of about 5,015,001 (272)

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

open access: yesInterdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang   +19 more
wiley   +1 more source

Isolation and characteristics of Shiga toxin 2f-producing Escherichia coli among pigeons in Kyushu, Japan. [PDF]

open access: yesPLoS One, 2014
Murakami K   +9 more
europepmc   +1 more source

Feature Subset Selection Algorithm for Clustering Using Modified Prim?s Algorithm

open access: yesInternational Journal of Scientific Engineering and Research, 2014
R Balakrishnan, M Soundarya
openaire   +1 more source

Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar   +11 more
wiley   +1 more source

Tumor haplotype assembly algorithms for cancer genomics. [PDF]

open access: yesPac Symp Biocomput, 2014
Aguiar D, Wong WS, Istrail S.
europepmc   +1 more source

An ultraviolet–visible spectroscopy system for studying real‐time pressure effects on enzyme activity

open access: yesLimnology and Oceanography: Methods, EarlyView.
Abstract Investigations of hydrostatic pressure effects on microbial enzymatic processing are challenging but critical for understanding element cycling in the world's oceans. In this study, we developed and tested a stainless‐steel pressure cell capable of withstanding up to 110 MPa of hydrostatic pressure (equivalent to ~ 11,000 m depth), featuring ...
Maria Papadimitraki   +6 more
wiley   +1 more source

Machine Learning Prediction of Raster Angle Effects on Mechanical Properties of Extrusion‐Based Additively Manufactured Conductive Thermoplastic Polyurethane Composites

open access: yesMacromolecular Materials and Engineering, EarlyView.
This study integrates machine learning (ML) and high‐fidelity experiments to model how raster angle influences the mechanical properties of fused filament fabricated conductive TPU composites. Using Poly6 and SVR models, the approach accurately predicts stiffness, strength, and ductility.
Imran Khan, Ans Al Rashid, Muammer Koç
wiley   +1 more source

Algorithms to model single gene, single chromosome, and whole genome copy number changes jointly in tumor phylogenetics. [PDF]

open access: yesPLoS Comput Biol, 2014
Chowdhury SA   +5 more
europepmc   +1 more source

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