Results 151 to 160 of about 5,015,001 (272)

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Towards an efficient compression of 3D coordinates of macromolecular structures. [PDF]

PLoS One, 2017
Valasatava Y, Bradley AR, Rose AS, Duarte JM, Prlić A, Rose PW.   +5 more
europepmc   +1 more source

Clinical Outcome Assessments in Parkinson's Disease: A Scoping Review of Current Rating Scales and Future Needs

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Clinical outcome assessments (COAs) are essential for evaluating symptom severity, treatment response, and disease progression in Parkinson's disease (PD). As clinical knowledge evolves, it is necessary to revisit the recommendation status on the COAs to ensure their continued relevance and validity. Objectives To provide an updated
Evita Papathoma, Panagiota Tsitsi, Nirosen Vijiaratnam, Camila Aquino, Stephen R. Duma, Norbert Kovacs, Kigocha Lameck Okeng'o, Aparna Wagle Shukla, Roongroj Bhidayasiri, Tiago A. Mestre, Alvaro Sanchez Ferro, Alberto J. Espay, Michelle H.S. Tosin, Matej Skorvanek, Ioanna Markaki   +14 more
wiley   +1 more source

Fast max-margin clustering for unsupervised word sense disambiguation in biomedical texts. [PDF]

BMC Bioinformatics, 2009
Duan W, Song M, Yates A.
europepmc   +1 more source

Preoperative VEGFR‐TKI Plus ICI Therapy Facilitates 3D‐Guided Cytoreductive Nephron‐Sparing Surgical Feasibility and Immune Remodeling in Advanced Renal Cell Carcinoma

Med Research, EarlyView.
Preoperative VEGFR‐TKI plus ICI therapy in advanced ccRCC normalizes tumor vasculature, enhances CD8⁺ T/B cell infiltration, and promotes TLS maturation, leading to profound tumor microenvironment remodeling. These immunologic changes improve the feasibility of 3D reconstruction‐guided robotic cytoreductive nephron‐sparing surgery, resulting in reduced
Wenhao Xu, Aihetaimujiang Anwaier, Qintao Ge, Siqi Zhou, Xi Tian, Shuxuan Zhu, Guohai Shi, Yu Zhu, Dingwei Ye, Mierxiati Abudurexiti, Hailiang Zhang   +10 more
wiley   +1 more source

Mapping cell populations in flow cytometry data for cross-sample comparison using the Friedman-Rafsky test statistic as a distance measure. [PDF]

Cytometry A, 2016
Hsiao C, Liu M, Stanton R, McGee M, Qian Y, Scheuermann RH.   +5 more
europepmc   +1 more source

Advances and Prospects of Stereotactic Radiosurgery and Stereotactic Ablative Body Radiotherapy: Evolving Paradigms in Precision Oncology

Med Research, EarlyView.
The graphical abstract outlines the progressive development and impact of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Technological Evolution illustrates the transition from brachytherapy with single‐dose, LDR/HDR schedules to fractionated radiotherapy, three‐dimensional conformal radiotherapy (3DCRT) and Gamma Knife ...
Jing Zhang, Wenhao Xu, Weiqing Lu, Yingxuan Lin, Luoxi He, Zonglin Lv, Yiliyaer Nuerrula, Zouting, Zhen Zhang, Hailiang Zhang, Xuejun Ma   +10 more
wiley   +1 more source

Exploring the full catalytic cycle of rhodium(i)-BINAP-catalysed isomerisation of allylic amines: a graph theory approach for path optimisation. [PDF]

Chem Sci, 2017
Yoshimura T, Maeda S, Taketsugu T, Sawamura M, Morokuma K, Mori S.   +5 more
europepmc   +1 more source

TopoMAS: Large Language Model Driven Topological Materials Multi‐Agent System

Materials Genome Engineering Advances, EarlyView.
TopoMAS is an interactive multi‐agent framework that revolutionizes topological materials discovery through human–AI collaborative intelligence. The system integrates natural language processing, knowledge retrieval from literature and databases, crystal structure generation, and automated first‐principles calculations within a unified workflow.
Baohua Zhang, Xin Li, Huangchao Xu, Zhong Jin, Quansheng Wu, Ce Li   +5 more
wiley   +1 more source

Robust lineage reconstruction from high-dimensional single-cell data. [PDF]

Nucleic Acids Res, 2016
Giecold G, Marco E, Garcia SP, Trippa L, Yuan GC.   +4 more
europepmc   +1 more source