Results 41 to 50 of about 5,015,001 (272)

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee   +9 more
wiley   +1 more source

Prim’s algorithm to model the pipe network at the water supply company

open access: yesJournal of Physics: Conference Series, 2019
It is the network in the water distribution already optimal, or does it form circuit instead? The circuit on the network will increase production costs which will have a direct impact on the price of the service.
M. S. Sinaga   +3 more
semanticscholar   +1 more source

Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss

open access: yesAdvanced Healthcare Materials, EarlyView.
Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan   +8 more
wiley   +1 more source

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao   +8 more
wiley   +1 more source

Applying Prim’s Algorithm to Identify Isolated Areas for Natural Disaster Prevention and Protection

open access: yes, 2018
Based on the principle of “pre-disaster prevention outweighs rescue during disasters”, this study targets areas threatened by natural disasters, and develops an automatic algorithm based on the Prim algorithm to serve as an automatic identification ...
Wen-Ching Wang   +2 more
semanticscholar   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad   +3 more
wiley   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra   +8 more
wiley   +1 more source

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister   +14 more
wiley   +1 more source

Specialized tabu search algorithm applied to the reconfiguration of radial distribution systems

open access: yesInternational Journal of Electrical Power & Energy Systems
This work presents a specialized tabu search algorithm applied to the problem of electric power distribution systems primary feeders’ reconfiguration. The specialization is related to two fundamental aspects of the tabu search algorithm.
Rafael Y. Yamamoto   +3 more
doaj   +1 more source

Progress and Prospects of Persistent Luminescent Nanocrystals in Biomedical Applications

open access: yesAdvanced Optical Materials, EarlyView.
This review summarizes recent progress in materials‐level control of persistent luminescence, including mechanistic understanding, wavelength/intensity tuning, and activation strategies, as well as emerging biomedical applications in imaging, biosensing, cell tracking, optogenetic stimulation, and biophotochemical activation.
Peng Pei   +5 more
wiley   +1 more source

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