Results 91 to 100 of about 955 (158)

Micro-RNAs, New performers in multiple myeloma bone marrow microenvironment [PDF]

, 2014

core   +1 more source

Targeting the p53/xCT/GSH Axis with PRIMA-1^Met Combined with Sulfasalazine Shows Therapeutic Potential in Chronic Lymphocytic Leukemia. [PDF]

Int J Mol Sci
Pasino M, Speciale A, Ravera S, Cutrona G, Massara R, Bertola N, Viale M, Velkova I, Mazzarello AN, Fais F, Loiacono F, Matis S, Valenti GE, Traverso N, Domenicotti C, Marengo B, Tasso B, Ibatici A, Angelucci E, Vaisitti T, Monti P, Menichini P.   +21 more
europepmc   +1 more source

Correction: PRIMA-1Met/APR-246 Displays High Antitumor Activity in Multiple Myeloma by Induction of p73 and Noxa [PDF]

Molecular Cancer Therapeutics, 2018
openaire   +2 more sources

[Corrigendum] PRIMA‑1^met induces autophagy in colorectal cancer cells through upregulation of the mTOR/AMPK‑ULK1‑Vps34 signaling cascade. [PDF]

Oncol Rep
Li XL, Zhou J, Xia CJ, Min H, Lu ZK, Chen ZR.   +5 more
europepmc   +1 more source

PRIMA-1(MET) induces death in soft-tissue sarcomas cell independent of p53. [PDF]

BMC Cancer, 2015
Grellety T, Laroche-Clary A, Chaire V, Lagarde P, Chibon F, Neuville A, Italiano A.   +6 more
europepmc   +1 more source

APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase. [PDF]

Cell Death Dis, 2013
Peng X, Zhang MQ, Conserva F, Hosny G, Selivanova G, Bykov VJ, Arnér ES, Wiman KG.   +7 more
europepmc   +1 more source

PRIMA-1 inhibits Y220C p53 amyloid aggregation and synergizes with cisplatin in hepatocellular carcinoma. [PDF]

Front Mol Biosci, 2023
Paz MM, Ferretti GDS, Martins-Dinis MMC, Ferreira BIS, Faier-Pereira A, Barnoud T, Moreira OC, Silva JL, Cordeiro Y, Rangel LP.   +9 more
europepmc   +1 more source

The Relationship between TP53 [PDF]

, 2018

core   +1 more source

Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET. [PDF]

Proc Natl Acad Sci U S A, 2013
Shalom-Feuerstein R, Serror L, Aberdam E, Müller FJ, van Bokhoven H, Wiman KG, Zhou H, Aberdam D, Petit I.   +8 more
europepmc   +1 more source

Variability in functional p53 reactivation by PRIMA-1(Met)/APR-246 in Ewing sarcoma. [PDF]

Br J Cancer, 2013
Aryee DN, Niedan S, Ban J, Schwentner R, Muehlbacher K, Kauer M, Kofler R, Kovar H.   +7 more
europepmc   +1 more source