Results 191 to 200 of about 1,796,462 (350)

Urinary neutrophil gelatinase-associated lipocalin in dogs: accuracy of a novel rapid test and biomarker behavior across clinical settings. [PDF]

J Vet Intern Med
Tagliasacchi F, Facchin A, Zambarbieri J, Cozzi M, Camelliti S, Lauzi S, Paltrinieri S, Giordano A, Scarpa P.   +8 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Subretinal Photovoltaic Implant to Restore Vision in Geographic Atrophy Due to AMD. [PDF]

N Engl J Med
Holz FG, Le Mer Y, Muqit MMK, Hattenbach LO, Cusumano A, Grisanti S, Kodjikian L, Pileri MA, Matonti F, Souied E, Stanzel BV, Szurman P, Weber M, Bartz-Schmidt KU, Eter N, Delyfer MN, Girmens JF, van Overdam KA, Wolf A, Hornig R, Corazzol M, Brodie F, Olmos de Koo L, Palanker D, Sahel JA.   +24 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Genome-wide association study of event-free survival in follicular lymphoma patients treated with front-line immunochemotherapy. [PDF]

Blood Cancer J
Ghesquières H, Drouet Y, Slager SL, Morschhauser F, Julia E, Galimberti S, Robinson D, Larson MC, Testard Q, Tesson B, Deleuze JF, Boland A, Thomas E, Lasset C, Novak AJ, Xerri L, Luminari S, Verney A, Laurent C, Rimsza LM, Habermann TM, Federico M, Link BK, Salles G, Cerhan JR.   +24 more
europepmc   +1 more source

La prima

, 1980
Esborrany del poema LXXXI de 'Los pasos del cazador'.
openaire   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Prolonged disease remission of the chronic immunological skin disorder hidradenitis suppurativa with adjunctive bacteriophage therapy. [PDF]

Nat Commun
Bens L, Vanhoutvin T, Green S, Gorivale S, Almeida M, Romaniuk F, Hillary T, Jansen D, Matthijnssens J, Vermeire S, Sabino J, Depypere M, Devolder D, Spriet I, Debaveye Y, De Munter P, Onsea J, Metsemakers WJ, van Noort V, Pirnay JP, Merabishvili M, Wagemans J, Lavigne R, Van Laethem A.   +23 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Comparative Analysis of Maintenance Treatments in Patients with Newly Diagnosed Advanced Ovarian Cancer After First-Line Platinum-Based Regimens. [PDF]

Cancers (Basel)
Gasperoni L, Cancanelli L, Ossato A, Del Bono L, Vecchia S, Fontanella C, Damuzzo V, Messori A.   +7 more
europepmc   +1 more source