Results 101 to 110 of about 37,714 (296)

Primary adrenal insufficiency

, 2021
Primary adrenal insufficiency is a rare condition caused by pathology of the adrenal gland itself, often due to autoimmune adrenalitis or inborn error of steroidogenesis. The adrenal cortex contains three zones, and each zone produces a different hormone - the zona glomerulosa (aldosterone), the zona fasciculata (cortisol), and the zona reticularis ...
openaire   +1 more source

Genetic aetiology of primary adrenal insufficiency in Chinese children [PDF]

, 2021
Zhuo Chang, Wei Lu, Zhuhui Zhao, Xi Li, Xiaojing Li, Rong Ye, Jinwen Ni, Pei Zhou, Miaoying Zhang, Ruoqian Cheng, Zhangqian Zheng, Chengjun Sun, Jing Wu, Feihong Luo   +13 more
openalex   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Case report of Primary Adrenal Insufficiency [PDF]

Perspectives In Medical Research
Addison's disease, also known as primary adrenal insufficiency (PAI), is a rare endocrine disorder characterized by a decrease in all three adrenal hormones. This case report describes a 32-year-old female who presented with generalized weakness, fatigue,
E Sandeep Reddy, Konda Chaitanya, Sesha Shailaja   +2 more
doaj   +1 more source

A case of primary bilateral adrenal lymphoma with partial adrenal insufficiency

Yonsei Medical Journal, 1999
Unilateral or bilateral non-Hodgkin's lymphomas arising primarily in the adrenal glands are extremely rare. These lymphomas are usually present with large, bilateral adrenal masses with or without lymphadenopathy, and may be accompanied by adrenal insufficiency in some cases.
K S, Lee, Y S, Chung, K H, Park, H S, Kim, H M, Kim   +4 more
openaire   +2 more sources

Behcet's disease presenting with primary hypothyroidism, adrenal insufficiency, and celiac disease: A case report [PDF]

, 2020
Ameer Kakaje, Rama Awad
openalex   +1 more source

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

Ashwagandha: Is It Safe? Part 1: A Regulatory Review

Phytotherapy Research, EarlyView.
ABSTRACT Over the last decade, ashwagandha (Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler, R. Al‐Mondhiry, L. Lang, R. Marles, M. Tallon, A. Raghu   +5 more
wiley   +1 more source

[Primary adrenal insufficiency in children].

Arquivos brasileiros de endocrinologia e metabologia, 2005
Primary adrenal insufficiency is a rare pediatric condition, which can be presented as chronic or acute forms, especially during stress. The clinical features are unspecific and include weakness, nausea and vomiting, abdominal pain and diarrhea, arterial hypotension, hypoglycemia and dehydration.
R S, Rijlaarsdam, M M L, van Diepen, J M, Wit   +2 more
openaire   +3 more sources

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source