Results 301 to 310 of about 92,601 (353)

The Utility of Plasma Metanephrines to Optimise Adrenal Vein Sampling for Primary Aldosteronism: A Single Centre Experience

Clinical Endocrinology, Volume 103, Issue 3, Page 294-302, September 2025.
ABSTRACT Background Primary aldosteronism (PA) is a prevalent yet frequently underdiagnosed cause of secondary hypertension, affecting up to 10% of hypertensive individuals and contributing to increased cardiovascular risk. Accurate diagnosis is vital, as unilateral PA cases typically require surgical intervention, while bilateral disease is managed ...
Zin Htut, Ali Alsafi, Aditi Sharma, Daniel Foran, Tricia Tan, Sophie C. Barnes, Emma L. Williams, Debbie Papadopoulou, Aimee Dimarco, Fausto Palazzo, Jeannie Todd, Rami Fikri, John Wass, Karim Meeran, Florian Wernig   +14 more
wiley   +1 more source

Low‐Dose Hydrocortisone in Cirrhotic Patients With Septic Shock: A Double‐Blind Randomised Placebo‐Controlled Trial

Liver International, Volume 45, Issue 9, September 2025.
ABSTRACT Background and Aims Steroid supplementation remains controversial in septic shock, partly due to the heterogeneity of the populations studied. Cirrhotic patients with sepsis frequently develop relative adrenal insufficiency, showing poor response to vasopressors and poor prognosis.
Philippe Meersseman, María Hernández‐Tejero, Juan Manuel Diaz, Joost Wauters, Greet Hermans, Fátima Aziz, Helga Ceunen, Veronica Prado, Lies Langouche, Mireya Arteaga, Juan Acevedo, Marc Lleixa, Juliana Zapatero, David Toapanta, Vicente Arroyo, Alexander Wilmer, Javier Fernandez   +16 more
wiley   +1 more source

Efficacy, Safety, Pharmacokinetics, and Immunogenicity of ABBV‐154 in Adults With Glucocorticoid‐Dependent Polymyalgia Rheumatica: A Phase 2, Randomized, Double‐Blind, Placebo‐Controlled Trial

Arthritis &Rheumatology, Volume 77, Issue 8, Page 1041-1051, August 2025.
Objective An unmet need exists for glucocorticoid‐sparing treatments for patients with polymyalgia rheumatica (PMR). The antibody‐drug conjugate ABBV‐154 comprises adalimumab conjugated to a glucocorticoid receptor modulator. We evaluated ABBV‐154 versus placebo in patients with glucocorticoid‐dependent PMR.
Robert F. Spiera, Valerie Devauchelle‐Pensec, Claire E. Owen, Federico Díaz‐González, Tsutomu Takeuchi, Edit Drescher, Jaclyn Anderson, Dilek Arikan, Ronilda D'Cunha, Julie Parmentier, Denise T. Kruzikas, Weihan Zhao, Yang Yang, Karen Stellpflug, Frank Buttgereit   +14 more
wiley   +1 more source

Primary adrenal insufficiency developed 22 years after the diagnosis of light and heavy chain deposition disease: a case report. [PDF]

CEN Case Rep
Eguchi E.
europepmc   +1 more source

Pharmacokinetics of betamethasone in pre‐eclampsia: An in vivo and ex vivo study

British Journal of Clinical Pharmacology, Volume 91, Issue 8, Page 2327-2339, August 2025.
Aims To enhance understanding of betamethasone and its metabolites' pharmacokinetics in pregnancy, specifically early‐onset pre‐eclampsia, through a population pharmacokinetic model. Additionally, to investigate the placental metabolism and transfer of betamethasone and its main metabolites.
Sam Schoenmakers, Letao Li, Anna C. M. Kluivers, Michelle Broekhuizen, Madhavi S. Harhangi, A. H. Jan Danser, Irwin Reiss, Karel Allegaert, Sjoerd A. A. van den Berg, Bertrand D. van Zelst, Ron H. N. van Schaik, Philip L. J. DeKoninck, Emma Ronde, Sebastiaan D. T. Sassen, Sinno H. P. Simons, Birgit C. P. Koch   +15 more
wiley   +1 more source

Use of Systemic Glucocorticoids and Risk of Prostate Adenocarcinoma: Evidence From a Danish Population‐Based Case–Control Study

Cancer Medicine, Volume 14, Issue 15, August 2025.
Use of systemic glucocorticoids and risk of prostate adenocarcinoma: Evidence from a Danish population‐based case–control study. ABSTRACT Background Glucocorticoids may promote prostate cancer by reducing apoptosis and the immune response, or prevent it by reducing inflammation, inhibiting androgens, and limiting cell proliferation.
Elea Olivier, Blánaid Hicks, Morten Olesen, Agnès Fournier, Gianluca Severi, Anton Pottegård, Manon Cairat   +6 more
wiley   +1 more source

Evaluation of Exercise Time and Cardiac Autonomic Responses with an Exercise Stress Test in Primary Adrenal Insufficiency

Süheyla Görar, Ziynet Alphan Üç, Görkem Kuş, İlhan Koyuncu, Emre Asiltürk, İsa Öner Yüksel, Erhan Köklü, Şakir Arslan   +7 more
openalex   +1 more source

Looking Inwards: The Role of Self‐Care, Self‐Management and Self‐Healing in Musculoskeletal Pain

Musculoskeletal Care, Volume 23, Issue 3, September 2025.
Joyce McSwan, Catherine E. Panwar, Ali Mobasheri   +2 more
wiley   +1 more source