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Fertility and pregnancy in women with primary adrenal insufficiency
Endocrine, 2020Primary adrenal insufficiency (PAI) occurs in ~1/5000-1/7000 individuals and is in most cases caused by autoimmune Addison's disease (AAD). Around 10-20% of women with AAD develop premature ovarian insufficiency (POI) before the age of 40 years. 21-Hydroxylase autoantibodies (21OHAb) are the best single immune marker to classify AAD among PAI patients ...
S. Bensing, R. Giordano, A. Falorni
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Pathogenesis of primary adrenal insufficiency
Best Practice & Research Clinical Endocrinology & Metabolism, 2009Autoimmune Addison's disease is caused by autoreactivity towards the adrenal cortex involving 21-hydroxylase autoantibodies and autoreactive T cells. Autoimmune destruction of the adrenal cortex is triggered by hitherto unknown environmental factors in individuals with genetic susceptibility.
Kristian Løvås, Eystein S. Husebye
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A case of cancer-associated hyponatraemia: primary adrenal insufficiency secondary to nivolumab.
Endocrine, Metabolic & Immune Disorders - Drug Targets, 2021BACKGROUND Immunotherapy with immune checkpoint inhibitors is a new frontier for cancer treatment. On the safety profile, this drug class is associated with a new spectrum of side effects, the so-called immune-related adverse events that can potentially ...
S. Galliazzo +4 more
semanticscholar +1 more source
Journal of Pediatric Endocrinology & Metabolism (JPEM), 2021
Objectives To describe an atypical presentation of primary adrenal insufficiency in conjunction with new onset type 1 diabetes. Case presentation Here, we describe a case of new-onset type 1 diabetes (T1D) presenting simultaneously with an unusual ...
Shelby Graf +4 more
semanticscholar +1 more source
Objectives To describe an atypical presentation of primary adrenal insufficiency in conjunction with new onset type 1 diabetes. Case presentation Here, we describe a case of new-onset type 1 diabetes (T1D) presenting simultaneously with an unusual ...
Shelby Graf +4 more
semanticscholar +1 more source
Pregnancies associated with primary adrenal insufficiency
Fertility and Sterility, 2008To provide a framework for the clinical presentation, evolution, treatment, and outcome of the unusual association between primary adrenal insufficiency (AI) during pregnancy and life-threatening complications for the mother and fetus.Case reports.Pregnant women with AI treated in the Endocrine and Diabetes Department, Hospital Universitario de ...
Paula Szafryk de Mereshian +3 more
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