Results 71 to 80 of about 4,700,345 (286)

Cardiomyopathy Associated With Tertiary Adrenal Insufficiency Manifesting as Refractory Heart Failure, Shock, and Sudden Cardiac Death: A Case Report

Frontiers in Cardiovascular Medicine, 2021
Dilated cardiomyopathy is an etiologically heterogeneous disorder. Early diagnosis and prompt treatment of the underlying disease are of great significance.
Xuefeng Wang, Yong Luo, Jian Feng
doaj   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

Advanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo, Joe G. Rizk, Emilia Calvano, Rajesh Sahu, Emina Colovic, Imane Chabba, Valentine Gilbart, Erwan Grandgirard, Bastien Morlet, Qingshuang Cai, Daniel Metzger, Delphine Duteil   +11 more
wiley   +1 more source

High prevalence of primary adrenal insufficiency in Zellweger spectrum disorders

, 2014
Zellweger spectrum disorders are a group of autosomal recessive disorders characterized by impaired peroxisome functions. The clinical spectrum is broad, ranging from the classical most severe Zellweger syndrome to patients with a relatively mild ...
Poll-The, Bwee Tien, Engelen, Marc, van Trotsenburg, A. S. Paul, Linthorst, Gabor E., Berendse, Kevin   +4 more
core   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Measurement of the adrenal cortex reserve using depot beta 1-24-corticotrophin. I--In adrenal insufficiency.

Acta Médica Portuguesa, 1979
Adrenal reserve was assessed by measuring plasma cortisol 4 and 6 hours after instramuscular injection of 1 mg Synacthen Depot in 87 normal subjects (95 tests), in 13 patients with primary adrenal insufficiency (26 tests) and in 21 patients with ...
A Galvão-Teles
doaj   +1 more source

Association Between Preoperative Steroid Use and Short‐Term Outcomes Following Pancreaticoduodenectomy: A Nationwide Analysis Using the National Clinical Database

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Pancreaticoduodenectomy (PD) carries a high risk of postoperative complications. Although steroids are widely prescribed for various chronic diseases, the specific impact after PD remains unclear. This study evaluated the association between preoperative chronic steroid use and short‐term outcomes following PD.
Yoshito Tomimaru, Hideki Endo, Hiroyuki Yamamoto, Teruhide Ishigame, Hideki Ueno, Ken Shirabe, Hidetoshi Eguchi   +6 more
wiley   +1 more source

Clinical insights of pregnancy management, adrenal insufficiency as a possible cause of elevated TSH: a pilot study of case series

BMC Pregnancy and Childbirth, 2023
Background The upper limit for thyroid-stimulating hormone has been strictly defined for pregnancy management, at which point levothyroxine replacement therapy will been initiated.
Ken Kanazawa, Tatsuro Inaba, Shinichiro Koga, Koichiro Kuwabara   +3 more
doaj   +1 more source

Simultaneous diagnosis of primary adrenal insufficiency and Type 1 diabetes mellitus

, 2023
Simultaneous diagnosis of primary adrenal insufficiency and Type 1 diabetes ...
T Espenschied (17098564), M Zacharin (13495291), Lawrence Gray (13080873), R Lawford (17098567)   +3 more
core  

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

Addison’s disease associated with hypokalemia: a case report

Journal of Medical Case Reports, 2021
Background Primary adrenal insufficiency (Addison's disease) is a rare medical condition usually associated with hyperkalemia or normokalemia. We report a rare case of Addison's disease, coexisting with hypokalemia, requiring treatment. Case presentation
M. Abdalla, J. A. Dave, I. L. Ross
doaj   +1 more source