Results 281 to 290 of about 4,814,966 (373)

The primary cilium is necessary for the differentiation and the maintenance of human adipose progenitors into myofibroblasts [PDF]

, 2017
Nicole Arrighi, K. Lypovetska, Claudine Moratal, Sophie Giorgetti‐Peraldi, Claude A. Dechesne, Christian Dani, Pascal Peraldi   +6 more
openalex   +1 more source

Does the primary cilium elongation play a role in urine concentration? [PDF]

Kidney Res Clin Pract
Kwon TH.
europepmc   +1 more source

Defining the Specialized Functions of cAMP Signals in an Organelle Formerly Deemed to Have No Function: The Primary Cilium. [PDF]

Function (Oxf), 2023
Hofer AM.
europepmc   +1 more source

Mechanobiology and Primary Cilium in the Pathophysiology of Bone Marrow Myeloproliferative Diseases. [PDF]

Int J Mol Sci
Tiberio F, Coda ARD, Tosi DD, Luzi D, Polito L, Liso A, Lattanzi W.   +6 more
europepmc   +1 more source

Biallelic Inactivating TUB Variants Cause Retinal Ciliopathy Impairing Biogenesis and the Structure of the Primary Cilium. [PDF]

Int J Mol Sci, 2022
Ziccardi L, Niceta M, Stellacci E, Ciolfi A, Tatti M, Bruselles A, Mancini C, Barbano L, Cecchetti S, Costanzo E, Cappa M, Parravano M, Varano M, Tartaglia M, Cordeddu V.   +14 more
europepmc   +1 more source

Supernumerary Centrosomes Nucleate Extra Cilia and Compromise Primary Cilium Signaling

, 2012
Moe R. Mahjoub, Tim Stearns
openalex   +1 more source

KIF9 Ameliorates Neuropathology and Cognitive Dysfunction by Promoting Macroautophagy in a Mouse Model of Alzheimer's Disease

Aging Cell, EarlyView.
KIF9 is downregulated in AD, accompanied by dysfunction in macroautophagy. Genetic upregulation of KIF9 enhances macroautophagy by promoting KLC1‐mediated anterograde transport of lysosomes, which effectively reduces Aβ deposition and alleviates cognitive impairments in AD.
Maoju Wang, Song Guo, Lilin Yi, Zhaolun Li, Xiuyu Shi, YePeng Fan, Man Luo, Yan He, Weihong Song, Yehong Du, Zhifang Dong   +10 more
wiley   +1 more source

Changes in expression of mesothelial BBS genes in 2D and 3D after lithium chloride and ammonium sulphate induction of primary cilium disturbance: a pilot study. [PDF]

Pharmacol Rep, 2023
Rouka E, Jagirdar RM, Sarrigeorgiou I, Pitaraki E, Sinis SI, Varsamas C, Papazoglou ED, Kotsiou OS, Lymberi P, Giannou A, Hatzoglou C, Gourgoulianis KI, Zarogiannis SG.   +12 more
europepmc   +1 more source

PKD2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium [PDF]

, 2017
Xiaowen Liu, Thuy N. Vien, Jingjing Duan, Shu‐Hsien Sheu, Paul G. DeCaen, David E. Clapham   +5 more
openalex   +1 more source

Transcriptional Heterogeneity and Differential Response of Rod Photoreceptor Pathway Uncovered by Single‐Cell RNA Sequencing of the Aging Mouse Retina

Aging Cell, EarlyView.
Healthy aging is accompanied by transcriptional dysregulation in retinal cells, leading to alterations in key molecular pathways and cellular responses, with the scotopic pathway being particularly affected. We show that rod photoreceptors, essential for initiating scotopic (low‐light) vision, exhibit selective vulnerability to aging‐associated ...
Laura Campello, Matthew J. Brooks, Benjamin R. Fadl, Hyo Sub Choi, Soumitra Pal, Anand Swaroop   +5 more
wiley   +1 more source