This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Nerve block or wound infiltration with liposomal bupivacaine for postoperative pain management in open orthopedic surgery: a meta-analysis of 38 randomized controlled trials involving 3,389 patients. [PDF]
Yu J +10 more
europepmc +1 more source
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Integration of Cardiovascular Disease Services within Primary Health Care Systems: Insights from South Asia. [PDF]
Collins JH +10 more
europepmc +1 more source
Effectiveness of a nurse-led telephonic brief intervention to reduce risky alcohol use among women in primary care in Brazil: a randomized controlled trial. [PDF]
Lima AVC +2 more
europepmc +1 more source
Comment on "A pragmatic trial evaluating the impact of the anumana clinical decision support tool for guideline-directed management of heart failure (ACT-HF): Clinical trial design and methods". [PDF]
Che B, Li L.
europepmc +1 more source
Prevention on Offense: How the Drug-Free Communities Program Drives National Strategy to Solidify a Drug-Free America. [PDF]
Carter S.
europepmc +1 more source
[The control of hypercholesterolemia in primary care].
X, Pintó Sala, C, Fiol Castaño
openaire +1 more source

