Results 31 to 40 of about 180,719 (248)

Energy system efficiency in Cuba de composition analysis of energy use and co2 emissions

open access: yesRevista Científica de Ingeniería Energética, 2023
This article presents results from a decomposition analysis of energy consumption and CO2 emissions in Cuba during the period 1971–2019. Energy decomposition is done with a dynamic Sun-Shapley decomposition, which produces activity ...
Jarmo Vehmas   +3 more
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Experimental and theoretical study on the thermal stability and pyrolysis mechanism of HCFO-1233 yd.(Z)

open access: yesResults in Chemistry
The thermal stability and decomposition mechanism of (Z)-1,1,1-trifluoro-3-chloroprop-2-ene (HCFO-1233 yd.(Z)) were systematically investigated through combined theoretical and experimental approaches.
Zhang Dongxin   +7 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Fuzzy k-Primary Decomposition of Fuzzy k-Ideal in a Semiring

open access: yesFuzzy Information and Engineering, 2015
In this paper, we establish that the Lasker–Noether theorem for a commutative ring may be generalized for a commutative semiring. We produce an example of an ideal in a Noetherian semiring which cannot be expressed as finite intersection of primary ...
S. Kar, S. Purkait, B. Davvaz
doaj   +1 more source

A New Hybrid Cryptocurrency Returns Forecasting Method Based on Multiscale Decomposition and an Optimized Extreme Learning Machine Using the Sparrow Search Algorithm

open access: yesIEEE Access, 2022
The return series of cryptocurrencies, which are emerging digital assets, exhibit nonstationarity, nonlinearity, and volatility clustering compared to other traditional financial markets, making them exceptionally difficult to forecast.
Xiaoxu Du   +4 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Simulation of thermal hazards risk in octogen based on non-isothermal DSC data

open access: yesScientific Reports, 2023
To evaluate the possible thermal risks associated with the storage of octogen (HMX), non-isothermal differential scanning calorimetry (DSC) experiments were conducted in order to ascertain the kinetic model and parameters governing its thermal ...
Zhi Wang   +10 more
doaj   +1 more source

Thermocatalytic Decomposition of Dimethyl Methylphosphonate Based on CeO2 Catalysts with Different Morphologies

open access: yesApplied Sciences, 2023
The catalytic performances of the catalysts and decomposition mechanisms of dimethyl methylphosphonate (DMMP), a commonly used nerve agent simulant, are well understood based on previous studies.
Weimin Kong   +6 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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