Results 151 to 160 of about 1,658,836 (295)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Assessment of Knowledge, Attitude, and Practice Towards the Prevention of Monkeypox Among People of Bangladesh With at Least Primary Education: A Cross-Sectional Study. [PDF]

Health Sci Rep
Raquib R, Tusher PC, Chowdhury AA, Islam O, Tipu JH, Talukder H, Uddin MM, Raquib A, Nath TC.   +8 more
europepmc   +1 more source

Impact of a cognitive stimulation program on the reading comprehension of children in primary education. [PDF]

Front Psychol, 2022
Reina-Reina C, Conesa PJ, Duñabeitia JA.   +2 more
europepmc   +1 more source

The Impact of Social Class Solidification on the Educational Opportunities of the Next Generation in the Philippines and the Barriers to Social Mobility in Primary Education

Marisol C. Muñoz-Carrasco
openalex   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Mapping the Evolution of Social and Emotional Learning Research in Primary Education Contexts: A Bibliometric and Thematic Analysis. [PDF]

J Intell
Alemdar M.
europepmc   +1 more source

Developmental Assessment of Visual Communication Skills in Primary Education. [PDF]

J Intell, 2022
Simon T, Biró I, Kárpáti A.
europepmc   +1 more source

Marc Depaepe. Order in Progress: Everyday Education Practicein Primary Schools - Belgium, 1880-1970. Leuven UniversityPress: Leuven, 2000.

, 2002
Sol Cohen
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Prevalence of risk for dyslexia, risk for dyscalculia, and their comorbidity in Spanish primary education: gender difference and socioeconomic status. [PDF]

Front Psychol
Loredo M, Luque JL, Giménez A, López-Pérez PJ.   +3 more
europepmc   +1 more source