Results 51 to 60 of about 7,822,772 (238)

Attention-dependent modulation of neural activity in primary sensorimotor cortex [PDF]

, 2013
Although motor tasks at most times do not require much attention, there are findings that attention can alter neuronal activity not only in higher motor areas but also within the primary sensorimotor cortex.
Nowak, Isabella, Müller, Notger Germar, Milnik, Annette   +2 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Coordinated Frequency Modulation Control Strategy of Wind Power and Energy Storage Considering Mechanical Load Optimization

Energies
When a doubly fed induction generator (DFIG) participates in primary frequency modulation by rotor kinetic energy control, the torque of the generator is changed sharply and the mechanical load pressure of the shaft increases rapidly, which aggravates ...
Chaoyu Zhang, Jiabin Li, Shiyi Liu, Peng Hu, Jiangzhe Feng, Haoyang Ren, Ruizhe Zhang, Jiaoxin Jia   +7 more
doaj   +1 more source

Simultaneous Travel and Hoist Maneuver Input Shaping Control Using Frequency Modulation

Shock and Vibration, 2017
This paper presents an input shaping control system for overhead crane operations involving simultaneous hoist and travel maneuvers. The control system utilizes model-based partial feedback linearization with frequency modulation.
Sameer Arabasi, Ziyad Masoud
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Control Strategy for Wind Farms-Energy Storage Participation in Primary Frequency Regulation Considering Wind Turbine Operation State

Energies
With the continuous improvement of wind power penetration in the power system, the volatility and unpredictability of wind power generation have increased the burden of system frequency regulation. With its flexible control mode and fast power adjustment
Linlin Yu, Jiafeng Wu, Yuming Cheng, Gaojun Meng, Shuyu Chen, Yang Lu, Ke Xu   +6 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Adaptive redundant residue number system coded multicarrier modulation

, 2000
The novel class of nonbinary maximum minimum distance redundant residue number system (RRNS) codes is invoked in the context of adaptively RRNS coded, symbol-by-symbol adaptive multicarrier modulation, in order to combat the effects of frequency ...
Liew, T.H., Keller, T., Hanzo, L.
core   +1 more source