Results 201 to 210 of about 578,199 (283)

Effectiveness of 13-week dialectical behavior therapy skills training for non-suicidal self-injury: a multi-center randomized clinical trial in China. [PDF]

Psychol Med
Ni F, Wu S, Liang M, Liu C, Zhang P, Zhang D, Rodriguez M, Glasenapp J, Yin C, Long J, Liu Y, Sun Y, Wu X, Liu G, Jiang X, Wang X, Lv H, Zhang Z, Wang S, Rosenthal Z, Wang C.   +20 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Autonomic Modulation and Body Composition in Educators: Physiological Associations in the Workplace Context. [PDF]

Brain Behav
Álvarez-Gallardo E, García AC, González-Sanz P, Belinchón-deMiguel P, Clemente-Suárez VJ.   +4 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Caffeine citrate increases ciliary beat frequency in human respiratory epithelial cells. [PDF]

Mol Cell Pediatr
Cindrić S, Bodenbeck L, Hjeij R, Loges NT, Edelbusch C, George S, Pennekamp P, Rieger-Fackeldey E, Omran H.   +8 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Wearable low-level laser therapy (laser acupuncture) versus manual acupuncture for chronic insomnia: protocol for a randomized, assessor-blinded, superiority trial. [PDF]

Front Psychiatry
Shen Y, Wen H, Kong T, Lin J, Chen A, Huang Y, Lin Y, Bin W.   +7 more
europepmc   +1 more source