Results 71 to 80 of about 1,382,969 (293)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Frequency dynamics during high CCGT and wind penetrations [PDF]
, 2011 Presented at AUPEC 2011, Australasian Universities Power Engineering Conference, Brisbane, Australia, 25 - 28 September 2011Frequency stability is the paramount concern for secure and reliable operation of a power system. High wind penetration levels are
Flynn, Damian, Meegahapola, Lasantha
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Analytical Approach for Novel Temporary Frequency Support Control of VSC HVDC
IEEE AccessThe grid support function by DC devices such as static synchronous compensator (STATCOM) or high-voltage direct current (HVDC) systems is becoming more important owing to renewable energy integration.
Junghun Lee, Minhan Yoon, Gilsoo Jang
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Primary Frequency Response by MTDC Offshore Grids [PDF]
, 2014 The preferred technology for connecting far from shore offshore wind plants to the onshore AC power system is the voltage-source converter based high voltage direct current (VSC-HVDC) transmission system.
Bucurenciu, A. (author)
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
IET Renewable Power Generation, 2021 The increasing penetration of renewable energy leads to the decrease of inertia and damping for replacing conventional power plants. The motor–generator pair (MGP) is proposed to improve inertial response and frequency regulation capability for the ...
Yujun Gu +6 more
doaj +1 more source