Results 1 to 10 of about 126,407 (290)

Primary graft dysfunction prevention strategies in the perioperative period [PDF]

JHLT Open
Background: Primary graft dysfunction (PGD) remains a leading cause of early morbidity and mortality after heart and lung transplantation. It results from a multifactorial process involving ischemia–reperfusion injury, inflammatory and immune responses ...
Jérémie Guillemin, MD, Michael Cutrone, DO, Suraj Yalamuri, MD, Monica Arndt, MD, Adrien Bouglé, MD, PhD, Sharon L. McCartney, MD, FASE   +5 more
doaj   +2 more sources

Primary graft dysfunction after lung transplantation. [PDF]

Curr Opin Organ Transplant, 2023
Purpose of review Primary graft dysfunction (PGD) is a clinical syndrome occurring within the first 72 h after lung transplantation and is characterized clinically by progressive hypoxemia and radiographically by patchy alveolar infiltrates.
Hunt ML, Cantu E.
europepmc   +3 more sources

Donor lung weight a novel predictor for primary graft dysfunction [PDF]

JHLT Open
Background: Primary graft dysfunction (PGD) remains a leading cause of early morbidity and mortality in lung transplantation. PGD is characterized by diffuse alveolar damage and the accumulation of extravascular lung water in the transplanted lung.
Andreas Martinsson, MD, Anders Thoren, MD, PhD, Sven-Erik Ricksten, MD, PhD, Jonatan Oras, MD, PhD, Moustafa Mohsen Abed, MD, Petra Vestlund, CTC, Jesper M. Magnusson, MD, PhD, Andreas Wallinder, MD, PhD   +7 more
doaj   +2 more sources

Primary graft dysfunction in heart transplantation: the challenge to survival [PDF]

Journal of Cardiothoracic Surgery
Primary graft dysfunction (PGD) is a life-threatening clinical condition with a high mortality rate, presenting as left, right, or biventricular dysfunction within the initial 24 h following heart transplantation, in the absence of a discernible ...
Hüseyin Sicim, Wing Sum Vincy Tam, Paul C. Tang   +2 more
doaj   +2 more sources

Primary Graft Dysfunction after LungTransplantation [PDF]

, 2014
__Abstract__ The human body requires oxygen to perform aerobic processes 1-3. The lungs are the respiratory organs that not only supply oxygen to the blood, but also remove carbon dioxide from the body.
Kaaij, N.P. (Niels) van der
core   +3 more sources

Primary graft dysfunction: what we know [PDF]

Journal of Thoracic Disease, 2021
Many advances in lung transplant have occurred over the last few decades in the understanding of primary graft dysfunction (PGD) though effective prevention and treatment remain elusive. This review will cover prior understanding of PGD, recent findings, and directions for future research.
Clausen, Emily, Cantu, Edward
openaire   +2 more sources

Primary Graft Dysfunction after Lung Transplantation [PDF]

Turkish Journal of Anaesthesiology and Reanimation, 2020
Primary graft dysfunction (PGD) is a severe form of acute lung injury that is a major cause of early morbidity and mortality encountered after lung transplantation. PGD is diagnosed by pulmonary oedema with diffuse alveolar damage that manifests clinically as progressive hypoxemia with radiographic pulmonary infiltrates.
Gülbin Töre, Altun, Mustafa Kemal, Arslantaş, İsmail, Cinel   +2 more
openaire   +2 more sources

Current status and outcomes in heart transplantation: a narrative review [PDF]

Reviews in Cardiovascular Medicine, 2022
The first human heart transplantation was performed by Christian Barnard in 1967. While the technical aspect had been worked out, allograft rejection was a major limitation in the early days of heart transplant.
Morcos A. Awad, Aakash Shah, Bartley P. Griffith   +2 more
doaj   +1 more source

Primary Graft Dysfunction [PDF]

Seminars in Respiratory and Critical Care Medicine, 2013
Primary graft dysfunction (PGD) is a syndrome encompassing a spectrum of mild to severe lung injury that occurs within the first 72 hours after lung transplantation. PGD is characterized by pulmonary edema with diffuse alveolar damage that manifests clinically as progressive hypoxemia with radiographic pulmonary infiltrates.
Yoshikazu, Suzuki, Edward, Cantu, Jason D, Christie   +2 more
openaire   +2 more sources

Reduction of primary graft dysfunction using cytokine adsorption during organ preservation and after lung transplantation

Nature Communications, 2022
Lung transplantation is hindered by the scarcity of organs and by mortality following primary graft dysfunction. Here, the authors show that cytokine absorption can be used in donor lungs during ex vivo lung perfusion and post-transplant, and leads to ...
Haider Ghaidan, Martin Stenlo, Anna Niroomand, Margareta Mittendorfer, Gabriel Hirdman, Nika Gvazava, Dag Edström, Iran A. N. Silva, Ellen Broberg, Oskar Hallgren, Franziska Olm, Darcy E. Wagner, Leif Pierre, Snejana Hyllén, Sandra Lindstedt   +14 more
doaj   +1 more source