Results 171 to 180 of about 20,558,786 (312)

Undergraduate nursing students' knowledge and attitudes towards Primary Health Care. [PDF]

PLOS Glob Public Health
Odeh N, Allari RS.
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Analysis of the implementation of nutritional care in the context of Primary Health Care. [PDF]

Rev Saude Publica
Machado PMO, Lacerda JT, Petrolini RS, Machado ML.   +3 more
europepmc   +1 more source

Primary Care Division Operational Plan 2017

, 2017
The Primary Care chapter of the 2017 National Service Plan (NSP) sets out the key priorities and volume of primary care, social inclusion, palliative care and primary care reimbursement services (PCRS) to be provided in 2017, within the funding available.
Primary Care Division. Health Service Executive.
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Primary Health Care Matters [PDF]

International Nursing Review, 2018
openaire   +2 more sources

Harnessing biotechnology and telemedicine for more equitable primary health care. [PDF]

Aten Primaria
Balocnit DA, Dayagon SPP, Lumines BB, Mabborang JM.   +3 more
europepmc   +1 more source

Implementing the primary health care approach: a synthesis of the primer

27 p.This publication synthesizes the main findings and messages of the WHO Primary Health Care (PHC) Primer, presenting the rationale, implementation mechanisms and system-wide impact of a PHC-oriented approach.
Winkelmann, Juliane, Figueras, Josep, Rajan, Dheepa, Dalil, Suraya, Kringos, Dionne, Khalid, Faraz, Lessof, Suszy, Rouleau, Katherine, Jakab, Melitta, Schmets, Gerard   +9 more
core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source