Results 231 to 240 of about 7,640,091 (402)

Artificial intelligence in supporting non-dental workers to integrate oral health into primary care: An integrative review [PDF]

Md. Nazmul Huda, Dileep Sharma, Sarbin Ranjitkar, Leonie Short, Wei Emma Zhang, Rahena Akhter, Poornima Ramamurthy, Padma Gadiyar, Basavaraj Patthi, Ajesh George   +9 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Continuity of care for people with hypertension in primary health care: a scoping review. [PDF]

Rev Esc Enferm USP
Ribeiro AMVB, Almeida PF, Vilasbôas ALQ.   +2 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Scope of Nursing Practice in Primary Health Care: defining a way forward. [PDF]

Rev Lat Am Enfermagem
Moreno-Dias B, Bolastig EVC, Puertas-Donoso EB.   +2 more
europepmc   +1 more source

Referee report. For: Determining staffing needs for improving primary health care service delivery in Kaduna State, Nigeria [version 1; peer review: 3 approved with reservations]

, 2022
Iboro Nelson
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Prices paid for primary health care medicines by Brazilian municipalities. [PDF]

Rev Saude Publica
Silva WROD, Cavalcanti ITDN, Peters JR, Ferreira LEMDS, Santana RS, Leite SN.   +5 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Impacts of continuing education for health professionals in primary health care: A scoping review. [PDF]

PLoS One
Pereira LKM, Adailton da Silva J, Feitosa EELC, Caitano AR, da Silva Valentim JLR, Romão MH, Batista NADN, Cortez LR, Coutinho KD, de Pinho Dias A, Lima TGFMS, Valentim RAM, Rosendo TS.   +12 more
europepmc   +1 more source