Results 291 to 300 of about 7,028,732 (403)

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Primary care and public health: Financial inducements to GPs sometimes inappropriate [PDF]

, 1993
David Hannay
openalex   +1 more source

Self-care practices of professionals on residency programs in the state of Paraíba in Brazil and their implications for primary health care. [PDF]

BMC Prim Care
Machado APR, de Fátima Diniz Souza É, de Oliveira JDL, de Oliveira JOD, Nóbrega LGS, Toscano MBR, Lacerda Massa NM, de Olinda RA, Tomaz AF, Medeiros CCM, Matheson D, Santos S.   +11 more
europepmc   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Growth Monitoring in the Context of a Primary Health Care Programme

, 1994
Fazlul Karim, Nasreen Huq, Laurine V. Brown, Rajiv Chowdhury   +3 more
openalex   +1 more source

Explaining outputs of primary health care: Authors' reply [PDF]

, 1991
Deborah Baker, R. Klein
openalex   +1 more source

Primary health care performance measurement at the service delivery level in Indonesia: a scoping review. [PDF]

BMC Health Serv Res
Solikha DA, Butler DC, Setiawan E, Korda RJ, Kelly M.   +4 more
europepmc   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Quality in Primary Health Care, Report of a Meeting held on 13th October, 1993 [PDF]

, 1994
William Reith
openalex   +1 more source

Beyond p‐values: Assessing clinical significance in acupuncture research

Advanced Chinese Medicine, EarlyView.
Abstract In acupuncture randomized controlled trials (RCTs), the proper interpretation of results requires a thorough understanding of key statistical concepts such as p‐value, effect size, and the minimal clinically important difference (MCID). This paper explores the relationships among these metrics and their implications for assessing the clinical ...
Changzhen Gong
wiley   +1 more source