Results 51 to 60 of about 29,467 (183)

Substernal oxyphil parathyroid adenoma producing PTHrP with hypercalcemia and normal PTH level

World Journal of Surgical Oncology, 2008
Background Parathyroid adenoma is the most common cause of primary hyperparathyroidism. Preoperative serum calcium and intact-parathyroid hormone levels are the most useful diagnostic parameters that allow differentiating primary hyperparathyroidism from
Rubini Domenico, Lippolis Agostino, Lissidini Germana, Marzullo Andrea, Gurrado Angela, Lastilla Gaetano, Testini Mario   +6 more
doaj   +1 more source

The Effect of Vitamin D3 Supplementation on the Risk of Falls in a General Population—The Finnish Vitamin D Trial

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background The impact of vitamin D on fall incidence remains controversial. We studied the effect of 5 years of vitamin D3 supplementation on the risk of falls in a double‐blind, placebo‐controlled randomized trial with generally healthy, community‐dwelling men and women in Finland.
Toni Rikkonen, Sari Hantunen, Heikki Kröger, Christel Lamberg‐Allardt, JoAnn E. Manson, Tarja Nurmi, Marjo Tuppurainen, Ari Voutilainen, Tomi‐Pekka Tuomainen, Jyrki K. Virtanen   +9 more
wiley   +1 more source

Effect of Two Therapeutic Renal Diets on Hormonal and Regulatory Pathways Affecting Calcium Homeostasis in Cats With Early‐Stage Chronic Kidney Disease

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall, Elizabeth M. Morris, Dale A. Fritsch, John J. Brejda, Kim M. Wilson   +4 more
wiley   +1 more source

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang, Geeta Madhuri Bhuvanagiri, Megan Dulkanchainun, Cunyu Wang   +3 more
wiley   +1 more source

Primary Hyperparathyroidism: lessons from two cases

Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche, 2019
Primary hyperparathyroidism (PHPT) is the most common cause of  hypercalcemia and is characterized by hypercalcemia and levels of parathyroid hormone (PTH) that are inappropriately high for the hypercalcemic state.
Giuseppe Turiano, Astrid Herberg
doaj   +1 more source

Representation, medical examination, and the effectiveness of underwriting: Evidence from a life and health insurance company

Risk Management and Insurance Review, EarlyView.
Abstract This study examines whether underwriting methods—representation, medical examination, extra premiums, and coverage—effectively mitigate adverse selection using data from an insurance company. Regarding representation, we focus on statements disclosing pre‐existing medical conditions.
Chia‐Ling Ho, Gene Lai, Chen‐Hsu Liao, Zifen Zeng   +3 more
wiley   +1 more source

Detection of renal tubular transporter proteins in canine urinary extracellular vesicles using liquid chromatography–tandem mass spectrometry

Veterinary Clinical Pathology, EarlyView.
Abstract Urinary extracellular vesicles (UEVs) are membranous particles that carry renal tubular transporter proteins. Here, we evaluate whether selected renal tubular transporter proteins can be detected in UEVs isolated from small volume (1–5 mL) canine urine samples of healthy dogs and canine patients with elevated circulating parathyroid hormone ...
L. J. McGravey, P. R. Antrobus, T. L. Williams   +2 more
wiley   +1 more source

Narushenie purinovogo obmena u patsienta s pervichnym giperparatireozom i sakharnym diabetom 2 tipa

Ожирение и метаболизм, 2010
In this article we describe a clinical case of primary hyperparathyroidism, gout tophus and diabetes mellitus type 2. The relationship between hyperuricemia and hypercalcemia linked to primary hyperparathyroidism is discussed.

doaj   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

Clinical presentation and outcome of surgical management of primary hyperparathyroidism: A single center-based case series in Egypt

Journal of Head & Neck Physicians and Surgeons, 2017
Introduction: Primary hyperparathyroidism is an asymptomatic disease in the Western world detected during routine laboratory investigations.The differential diagnosis and the management of primary hyperparathyroidism presenting with more severe symptoms ...
Hebatallah Gamal El Din Mohamed Mahmoud
doaj   +1 more source