Results 51 to 60 of about 4,325,288 (187)

Cranio-osteoarthropathy in sibs

, 2007
Primary hypertrophic osteoarthropathy is a condition characterized by clubbing, arthropathy and periostosis of long tubular bones. Three variants of primary hypertrophic osteoarthropathy are distinguished: pachydermoperiostosis, which shows as additional
Hennekam, Raoul C. M., Hall, Christine M., Wilson, Louise C., Dabir, Tabib, Sills, A. M., Bennett, Chris   +5 more
core   +1 more source

A Case Study of a Female Infant With Primary Hypertrophic Osteoarthropathy Demonstrates That Early Initiation of Celecoxib Slows but Does Not Prevent Symptom Progression

American Journal of Medical Genetics Part A, Volume 197, Issue 5, May 2025.
ABSTRACT Primary Hypertrophic Osteoarthropathy (PHOAR1) is characterized by autosomal recessive loss of function variants in 15‐hydroxyprostaglandin dehydrogenase (HPGD) leading to digital clubbing, periostosis, pachydermia, and severe hyperhidrosis. HPGD catalyzes the first step of prostaglandin E2 (PGE2) degradation.
Kara Zehr, Morgan Buckley, Joshua W. Owens, Tomas Vanagunas, Patricia Vega Fernandez, Robert J. Hopkin, Amelle Shillington   +6 more
wiley   +1 more source

Hypertrophic osteoarthropathy as a paraneoplastic manifestation of lung cancer. [PDF]

, 2020
Hypertrophic osteoarthropathy (HOA) is a syndrome that consists of periostitis, digital clubbing, and painfulpolyarthropathy. The management and prognosis of HOA is dependent on the underlying disease process.Recognising and treating it accordingly will ...
Rutkowski, Marcin; Oddział Kliniczny Pulmonologii, Alergologii, Chorób Wewnętrznych Szpitala Uniwersyteckiego w Krak owie, Poland, Picco Brunetto, Alba Gabriela; Hospital San Juan de Dios, Calle Beloso Alto 3, 31006 Pamplona, Spain, Masłowska, Aleksandra; Oddział Kliniczny Pulmonologii, Alergologii, Chorób Wewnętrznych Szpitala Uniwersyteckiego w Krak owie, Poland   +2 more
core   +1 more source

Cystic fibrosis dermatitis arthritis syndrome: A series of four cases

Pediatric Dermatology, Volume 42, Issue 1, Page 133-135, January/February 2025.
Abstract Dermatologic manifestations of cystic fibrosis (CF) include nutrient deficiency dermatoses, vasculitis, transient reactive papulotranslucent acrokeratodema, digital clubbing, and increased rates of atopy and drug reactions. Few cases of a characteristic eruption in patients with episodic arthritis of CF have been described with prior reports ...
Gabrielle Schwartzman, Barrett J. Zlotoff, Alejandro A. Gru, Darren J. Guffey   +3 more
wiley   +1 more source

Primary Hypertrophic Osteoarthropathy: A Case Report

Case Reports in Clinical Practice, 2018
The primary hypertrophic osteoarthropathy (PHOA or pachydermoperiostosis) is a rare (5% of total HOA) hereditary disease. One study described that the prevalence of PHOA is 0.16%.
Shima Asadi-Komeleh, Abdolrahman Rostamian, Fatemeh Shahbazi, Shafieh Movassagi, Parviz Soofivand   +4 more
doaj  

Rheumatic manifestations associated with lung diseases [PDF]

Einstein (São Paulo), 2008
Rheumatic manifestations in the more prevalent lung diseasessuch as asthma, chronic pulmonary disease or pneumonia are notfrequent. Exceptions to this rule are represented by lung cancerand sarcoidosis, where the appearance of the digital clubbing ...
Marco Aurelio Scarpinella Bueno, Hélio Romaldini   +1 more
doaj  

Osteoartropatia hipertrófica idiopática: relato de caso e revisão da literatura Primary hypertrophic osteoarthropathy: case report and literature review

Revista Brasileira de Reumatologia, 2009
A osteoartropatia hipertrófica primária é uma síndrome rara, caracterizada pela presença de baqueteamento digital de mãos e pés, aumento das extremidades e de tecidos periarticulares secundários à proliferação óssea, fisionomia facial grosseira, dor e ...
Aline Biral Zanon, Mellysande Pontes Faccin, Sônia Maria Alvarenga Anti, Felipe José Silva Melo Cruz, Renata Ferreira Rosa   +4 more
doaj   +1 more source

An Aggressive Case of Thymic Lymphoepithelial Carcinoma Complicated by Cytokine Release Syndrome: A Case Report

Case Reports in Oncological Medicine, Volume 2025, Issue 1, 2025.
Thymic lymphoepithelial carcinomas (TLECs) are a rare primary thymic cancer best described by lymphoplasmacytic infiltration of the thymic stroma. Though only accounting for 1.3%–6% of thymic carcinomas, the distribution of TLECs is bimodal, peaking around ages 14 and 48 and affecting males to females in a 2:1 ratio.
Louis G. Filipiak, Nyembezi L. Dhliwayo, Koosha Paydary, Jose I. Mayordomo   +3 more
wiley   +1 more source

Pulmonary hypertrophic osteoarthropathy in a child with late-onset agammaglobulinemia

, 1982
A case of hypertrophic osteoarthropathy is described in an 8-year-old child with late-onset agammaglobulinemia, bronchiectasis and clubbing of the fingers and toes.
MONAFO V, BELUFFI G, RE R, MARSEGLIA, GIAN LUIGI, UGAZIO AG, MARTINI A   +5 more
core   +1 more source

Changes in Nucleus Pulposus Cell Atlas and the Role of SPP1 During Intervertebral Disc Degeneration: Single‐Cell Sequencing Analysis

Mediators of Inflammation, Volume 2025, Issue 1, 2025.
Background The nucleus pulposus (NP) plays a central role in the pathogenesis of intervertebral disc degeneration (IVDD); however, its internal cellular heterogeneity and molecular mechanisms have not yet been elucidated. Methods ScRNA‐seq was used to evaluate the structure of the NP at different degenerative stages in the same individual with IVDD ...
Chen Liu, Kun Jiao, Xiaoyu Li, Zixiang Deng, Shanhe Wang, Yajun Cheng, Ming Li, Xiaoyi Zhou, Xianzhao Wei, Jingru Tian   +9 more
wiley   +1 more source