Results 301 to 310 of about 298,517 (337)

Primary Immunodeficiencies of Horses

Veterinary Clinics of North America: Equine Practice, 2000
Primary immunodeficiency disorders are genetically determined failures of immune defense that increase susceptibility to infectious agents. This article reviews the salient features of equine primary immunodeficiency disorders, summarizes the molecular mechanisms of each disorder, and updates information that facilitates diagnosis and management of ...
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Primary Immunodeficiency Syndromes

2010
Several DNA repair pathways have evolved to recognise and repair DNA damaged by exogenous and endogenous agents, in order to maintain genomic integrity. Defects in these pathways can lead to replication errors, loss or rearrangement ofgenomic material, mutation or cancer and eventual death.
Mary Slatter, Andrew R. Gennery
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Immunodeficiency and Multiple Primary Malignancies [PDF]

, 2009
The relationship between cancer onset and the immune response became a subject of great interest in the early 1900s, and led Ehrlich [1] to establish what came to be known as the theory of immunological surveillance. This theory is based on three principles: (1) cancer cells are antigenic, (2) these cells can be destroyed by the immune response of the ...
SANTANGELO, MICHELE, Spiezia S., Clemente M., RENDA, ANDREA, GENOVESE, ARTURO, SPADARO, GIUSEPPE, D’Orio C., MARONE, GIANNI, Federico S., Sabbatini M., Rotaia E., Piselli P., Cimaglia C., Serraino D.   +13 more
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Primary cellular immunodeficiencies

Journal of Allergy and Clinical Immunology, 2002
Genetic defects in T-cell function lead to susceptibility to infections or to other clinical problems that are more grave than those seen in disorders resulting in antibody deficiency alone. Those affected usually present during infancy with either common or opportunistic infections and rarely survive beyond infancy or childhood. The spectrum of T-cell
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Primary Immunodeficiency in the NICU

NeoReviews, 2019
Primary immunodeficiency disorders (PIDs) are genetic diseases that lead to increased susceptibility to infection. Hundreds of PIDs have now been described, but a select subset commonly presents in the neonatal period. Neonates, especially premature newborns, have relative immune immaturity that makes it challenging to differentiate PIDs from intrinsic
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Primary Immunodeficiency Diseases

JAMA: The Journal of the American Medical Association, 1997
Primary immunodeficiencies are rare, but important for 3 reasons. First, a high index of suspicion and prompt diagnosis can lead to lifesaving treatment or significant improvement in quality of life. Second, appreciation of the genetic nature of a host defense defect makes possible family counseling and carrier and prenatal diagnosis.
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Cervical cancer prevention and control in women living with human immunodeficiency virus

Ca-A Cancer Journal for Clinicians, 2021
Philip E Castle, Vikrant V Sahasrabuddhe, Philip E Castle   +2 more
exaly  

EBV‐positive B‐cell lymphomas and lymphoproliferative disorders: Review from the perspective of immune escape and immunodeficiency

Cancer Medicine, 2021
Akira Satou
exaly  

Primary Immunodeficiency

Pediatric Clinics of North America, 1974
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Enhancing global access to cancer medicines

Ca-A Cancer Journal for Clinicians, 2020
Javier Cortés, Giuseppe Curigliano, Nagi El-saghir   +2 more
exaly