Results 151 to 160 of about 637 (174)

MASH Background Confers Enhanced Disease Susceptibility and Acetaminophen Toxicity in iPSC‐Derived Liver Organoids

Advanced Science, EarlyView.
This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha, Ashwani Kumar Gupta, Nate Schmidt, Richard M. Green, John G. Purdy, Jason A. Wertheim   +5 more
wiley   +1 more source

Greener Decellularization of Porcine Auricular Cartilage Using Supercritical Technology and Different Pretreatments for Application in Tissue Engineering. [PDF]

ACS Biomater Sci Eng
de Souza VM, Zuliani CC, da Cunha JB, Carron J, Lima CSP, Coimbra IB, Rosa PTV, Moraes ÂM.   +7 more
europepmc   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

CRISPR and Artificial Intelligence in Neuroregeneration: Closed-Loop Strategies for Precision Medicine, Spinal Cord Repair, and Adaptive Neuro-Oncology. [PDF]

Int J Mol Sci
Șerban M, Toader C, Covache-Busuioc RA.
europepmc   +1 more source

Is there evidence for the use of lesion sterilization and tissue repair therapy in the endodontic treatment of primary teeth? A systematic review and meta-analyses

Clinical Oral Investigations, 2020
Andrea Vaz Braga Pintor, Neves Aa, Maia Lc   +2 more
exaly  

Consistent Query Answering for Self-Join-Free Conjunctive Queries Under Primary Key Constraints

ACM Transactions on Database Systems, 2017
Jef Wijsen
exaly  

Soft‐tissue sarcoma in adults: An update on the current state of histiotype‐specific management in an era of personalized medicine

Ca-A Cancer Journal for Clinicians, 2020
Alessandro Gronchi, Adriana Gamboa, Kenneth Cardona   +2 more
exaly  

Certain conjunctive query answering in first-order logic

ACM Transactions on Database Systems, 2012
Jef Wijsen
exaly  

Autoimmunity: Attack, or Defence? (The Case for a Primary Lesion Theory)

Autoimmunity, 1989
T Wilkin
exaly  

Early Diagnosis of Oral Cancer: The Erythroplastic Lesion in High Risk Sites

Ca-A Cancer Journal for Clinicians, 1978
A Mashberg, L Garfinkel
exaly