Results 21 to 30 of about 890,728 (306)

Liver Development, Regeneration, and Carcinogenesis [PDF]

, 2010
The identification of putative liver stem cells has brought closer the previously separate fields of liver development, regeneration, and carcinogenesis. Significant overlaps in the regulation of these processes are now being described.
Ross, James A, Kung, Janet W C, Currie, Ian S, Stuart J. Forbes, Forbes, Stuart J, Janet W. C. Kung, Ian S. Currie, James A. Ross   +7 more
core   +1 more source

Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival

BMC Gastroenterology, 2008
Background The tumour suppressor phosphatase and tensin homolog (PTEN) is an important negative regulator of cell-survival signaling. To evaluate the correlation between PTEN expression and clinicopathological characteristics of colorectal cancer ...
Funahashi Hitoshi, Takahashi Hiroki, Wakasugi Takehiro, Matsuo Yoichi, Ma Jiachi, Ochi Nobuo, Yasuda Akira, Sawai Hirozumi, Sato Mikinori, Takeyama Hiromitsu   +9 more
doaj   +1 more source

Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway [PDF]

, 2015
Background: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths, reflecting the aggressiveness of this type of cancer and the absence of effective therapeutic regimens.
Drakaki, A, Dimitrios Iliopoulos, Drakaki, Alexandra, Maria Hatziapostolou, Iliopoulos, Dimitrios, Georgoulias, V, Vassilis Georgoulias, Hatziapostolou, M, Alexandra Drakaki, Christos Polytarchou, Vorvis, Christina, Polytarchou, Christos, John Souglakos, Georgoulias, Vassilis, Poultsides, George A, Poultsides, GA, Iliopoulos, D, Hatziapostolou, Maria, George A. Poultsides, Souglakos, J, Vorvis, C, Souglakos, John, Christina Vorvis, Polytarchou, C   +23 more
core   +1 more source

A Changing Paradigm for the Treatment of Intermediate-Stage Hepatocellular Carcinoma: Asia-Pacific Primary Liver Cancer Expert Consensus Statements [PDF]

, 2020
The Asia-Pacific Primary Liver Cancer Expert (APPLE) Consensus Statement on the treatment strategy for patients with intermediate-stage hepatocellular carcinoma (HCC) was established on August 31, 2019, in Sapporo, Hokkaido during the 10th Annual APPLE ...
한광협
core   +1 more source

DNA Methylation and Hydroxymethylation in Primary Colon Cancer and Synchronous Hepatic Metastasis

Frontiers in Genetics, 2018
Colon cancer is one of the most frequent solid tumor and simultaneous diagnosis of primary colon cancer and liver metastases occurs in about one fourth of cases.
Silvia Udali, Domenica De Santis, Andrea Ruzzenente, Sara Moruzzi, Filippo Mazzi, Greta Beschin, Stephanie A. Tammen, Tommaso Campagnaro, Patrizia Pattini, Oliviero Olivieri, Alfredo Guglielmi, Sang-Woon Choi, Sang-Woon Choi, Simonetta Friso   +13 more
doaj   +1 more source

A Paradigm Shift in Primary Liver Cancer Therapy Utilizing Genomics, Molecular Biomarkers, and Artificial Intelligence

, 2023
Primary liver cancer is the sixth most common cancer worldwide and the third leading cause of cancer-related death. Conventional therapies offer limited survival benefit despite improvements in locoregional liver-directed therapies, which highlights the ...
James Moroney, Juan Trivella, Ben George, Sarah B. White   +3 more
core   +1 more source

Pre-diagnostic anti-EBV antibodies and primary liver cancer risk: a population-based nested case-control study in southern China

BMC Cancer, 2023
Background We aimed to investigate associations between pre-diagnostic anti-Epstein-Barr virus (EBV) antibodies, including interactions with hepatitis B virus (HBV), and risk of primary liver cancer in southern China. Methods In a population-based nested
Yun Du, Xia Yu, Ellen T. Chang, Shifeng Lian, Biaohua Wu, Fugui Li, Bing Chu, Kuangrong Wei, Jiyun Zhan, Xuejun Liang, Weimin Ye, Mingfang Ji   +11 more
doaj   +1 more source

Association of early age at establishment of chronic hepatitis B infection with persistent viral replication, liver cirrhosis and hepatocellular carcinoma: a systematic review. [PDF]

, 2013
Age at infection with hepatitis B virus (HBV) is a known risk factor for chronic HBV infection. However, in addition, there is some evidence that early age at infection further increases the risk of primary liver cancer beyond its association with ...
Bottomley, Christian, Andrew J Hall, Hong-Jing Yan, Tsuchiya Naho, Hall, Andrew, Andrew J. Hall (78002), Shimakawa Yusuke, Yan, Hong-Jing, Yusuke Shimakawa, Christian Bottomley, Hall Andrew J., Hall, Andrew J, Yan Hong-Jing, Shimakawa, Yusuke, Tsuchiya, Naho, Naho Tsuchiya, Bottomley Christian, Andrew J. Hall, Yusuke Shimakawa (435296), Hong-Jing Yan (435297), Naho Tsuchiya (211103), Christian Bottomley (144483)   +21 more
core   +1 more source

RESULTS RENTGENENDOVASCULAR METHODS OF THE TREATMENT OF NEOPLASTIC LESIONS OF LIVER IN SOUTH KAZAKHSTAN

Креативная хирургия и онкология, 2017
In clause results endovascular methods of treatment of 70 patients with tumoral defeats of a liver of men 47 (67,1 %), women 23 (32,9 %), from them are presented: a primary cancer of a liver 42 (60 %) cases, metastatic defeats of a liver 28 (40 %). Chemo-
K. Sh. Gantsev, D. T. Arybzhanov, Sh. Kh. Gantsev, B. V. Besedin   +3 more
doaj   +1 more source

Liver transplantation for primary and metastatic liver cancers [PDF]

Transplant International, 2008
Liver transplantation for hepatic malignancies has emerged as a well-documented and proven treatment modality. However, early unsatisfactory results emphasized that only a highly selected patient population would benefit from transplantation. Currently, 15% of all liver transplants performed are for hepatocellular carcinoma (HCC).
Emir, Hoti, Rene, Adam
openaire   +2 more sources