Results 241 to 250 of about 4,637,348 (295)

A conducive clinical learning environment in primary care as a wicked problem: A scoping review of enablers, obstacles, and strategies. [PDF]

Afr J Prim Health Care Fam Med
Eales O, Brits H, Lubbe I, Moyo-Chilufya M, Van Rooyen M.   +4 more
europepmc   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

From matching to facilitation: Reframing AI's role in clinical trial enrollment. [PDF]

Patterns (N Y)
Yaacov A, Levi E, Peled N.
europepmc   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

Enhancing HIV commodity reporting using real-time antiretrovirals stock status monitoring tool in an HIV-accredited regional referral hospital, Kampala, March 2024 - August 2024. [PDF]

J Public Health Afr
Rutogire TM, Gidudu S, Bahizi G, Were J, Kyamwine IB, Bulage L, Ario AR.   +6 more
europepmc   +1 more source

Data‐Driven Modeling of Composition–Processing–Microstructure Relations for Recycled Aluminum Cast Alloys

Advanced Science, EarlyView.
Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang, Waleed Mohammed, Dierk Raabe   +2 more
wiley   +1 more source

The hidden costs of technical advancements: software and equipment troubleshooting in robotic inguinal hernia repair. [PDF]

J Surg Case Rep
Martin C, Howells C.
europepmc   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Integrating Primary Health Care into Flexible Surge Capacity: Bridging the Subnational "Missing Middle" in Health Emergency Preparedness. [PDF]

Healthcare (Basel)
Khorram-Manesh A.
europepmc   +1 more source

Beyond living donation: robot-assisted kidney transplantation using deceased-donor grafts-a scoping review of selection, ischaemia logistics, and allograft outcomes. [PDF]

J Robot Surg
Drobot RB, Domel T, Lipa M, Ludwiczak D.
europepmc   +1 more source