Results 11 to 20 of about 4,811,177 (246)

Focus on Osteosclerotic Progression in Primary Myelofibrosis [PDF]

Biomolecules, 2021
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm characterized by hematopoietic stem-cell-derived clonal proliferation, leading to bone marrow (BM) fibrosis. Hematopoiesis alterations are closely associated with modifications of the BM microenvironment, characterized by defective interactions between vascular and endosteal niches.
Spampinato, Mariarita, Giallongo, Cesarina, Romano, Alessandra, Longhitano, Lucia, La Spina, Enrico, Avola, Roberto, Scandura, Grazia, Dulcamare, Ilaria, Bramanti, Vincenzo, Di Rosa, Michelino, Vicario, Nunzio, Parenti, Rosalba, Li Volti, Giovanni, Tibullo, Daniele, Palumbo, Giuseppe A   +14 more
openaire   +5 more sources

Targeted deep sequencing in primary myelofibrosis [PDF]

Blood Advances, 2016
Key Points More than 80% of patients with PMF harbor DNA variants/mutations other than JAK2/CALR/MPL. Some of these variants/mutations adversely affect overall or leukemia-free survival independent of conventional risk stratification.
Animesh Pardanani, Terra L. Lasho, Curtis A. Hanson, Yoseph Elala, Christy Finke, Naseema Gangat, Rhett P. Ketterling, Ayalew Tefferi   +7 more
openaire   +5 more sources

A Case of Primary Autoimmune Myelofibrosis [PDF]

Korean Journal of Medicine, 2014
Primary autoimmune myelofibrosis, the development of which is not preceded by a well-defined autoimmune disease, has recently been defined as a distinct clinicopathologic syndrome. We report herein a case of a 68-year-old woman who was diagnosed with primary autoimmune myelofibrosis and present a review of the literature.
Yeong‐Min Lim, Chi Young Park, Won jung Hong, Gwangil Kim, So-Young Chong, Doyeun Oh   +5 more
openalex   +3 more sources

Primary myelofibrosis: current therapeutic options

Revista Brasileira de Hematologia e Hemoterapia, 2016
Primary myelofibrosis is a Philadelphia-negative myeloproliferative neoplasm characterized by clonal myeloid expansion, followed by progressive fibrous connective tissue deposition in the bone marrow, resulting in bone marrow failure.
Paula de Melo Campos
doaj   +5 more sources

Does angiogenesis matter in primary myelofibrosis?

Revista Brasileira de Hematologia e Hemoterapia, 2014
Primary myelofibrosis(PMF)isaclonalhematopoieticdisordercharacterized by an initial prefibrotic proliferative phase thatover time progresses to bone marrow fibrosis, extramedullaryhematopoiesis, peripheral blood cytopenias and an increasedrisk of developing acute myeloid leukemia (AML).
Paulo Vidal Campregher
openalex   +6 more sources

Involvement of TGFβ1 in autocrine regulation of proplatelet formation in healthy subjects and patients with primary myelofibrosis

Haematologica, 2013
Megakaryocytes release platelets into the bloodstream by elongating proplatelets. In this study, we showed that human megakaryocytes constitutively release Transforming Growth Factor β1 and express its receptors.
Stefania Badalucco, Christian Andrea Di Buduo, Rita Campanelli, Isabella Pallotta, Paolo Catarsi, Vittorio Rosti, David L. Kaplan, Giovanni Barosi, Margherita Massa, Alessandra Balduini   +9 more
doaj   +3 more sources

Primary myelofibrosis: spectrum of imaging features and disease-related complications

Insights into Imaging, 2019
Primary myelofibrosis is a chronic clonal stem cell disorder that results in a build-up of marrow fibrosis and dysfunction, hypermetabolic states, and myeloid metaplasia.
Sheng Fei Oon, Dalveer Singh, Teng Han Tan, Allan Lee, Geertje Noe, Kate Burbury, Joseph Paiva   +6 more
doaj   +2 more sources

Treatment of myelofibrosis and primary erythermalgia [PDF]

American Journal of Hematology, 1993
Şînasi Özsoylu
openalex   +3 more sources

Extramedullary myeloid tumors in primary myelofibrosis [PDF]

Cancer, 1965
Philip Lieberman, Randi V. Rosvoll, Allyn B. Ley   +2 more
openalex   +4 more sources

Is it primary myelofibrosis or chronic megakaryocytic leukemia? [PDF]

Haematologica, 2022
Lichtman MA.
europepmc   +4 more sources