Results 11 to 20 of about 4,315,874 (223)

Primary myelofibrosis

, 2010
Myelofibrosis is a reactive process common to many malignant and benign disorders. Primary myelofibrosis is a chronic myeloproliferative disorder of unknown aetiology that involves a multipotent haemopoietic progenitor cell and results in abnormalities ...
Jerry L. Spivak
core   +3 more sources

Tetraspanin CD9 participates in dysmegakaryopoiesis and stromal interactions in primary myelofibrosis [PDF]

Haematologica, 2015
Primary myelofibrosis is characterized by clonal myeloproliferation, dysmegakaryopoiesis, extramedullary hematopoiesis associated with myelofibrosis and altered stroma in the bone marrow and spleen.
Christophe Desterke, Christophe Martinaud, Bernadette Guerton, Lisa Pieri, Costanza Bogani, Denis Clay, Frederic Torossian, Jean-Jacques Lataillade, Hans C. Hasselbach, Heinz Gisslinger, Jean-Loup Demory, Brigitte Dupriez, Claude Boucheix, Eric Rubinstein, Sophie Amsellem, Alessandro M. Vannucchi, Marie-Caroline Le Bousse-Kerdilès   +16 more
doaj   +2 more sources

Primary autoimmune myelofibrosis: A case report in a child

eJHaem, 2020
Autoimmune myelofibrosis (AIMF) is an uncommon cause of myelofibrosis associated with favorable outcome. Primary AIMF, AIMF without a known systemic autoimmune disorder, has been described in adults, but never in children. Here, we present, for the first
Zufit Hexner‐Erlichman, Joanne Yacobovich, Philippe Trougouboff, Moran Avraham‐Kelbert, Harel Eitam, Ronen Spiegel, Shay Yeganeh, Carina Levin   +7 more
doaj   +2 more sources

Primary myelofibrosis: current therapeutic options [PDF]

Revista Brasileira de Hematologia e Hemoterapia, 2016
Primary myelofibrosis is a Philadelphia-negative myeloproliferative neoplasm characterized by clonal myeloid expansion, followed by progressive fibrous connective tissue deposition in the bone marrow, resulting in bone marrow failure.
Paula de Melo Campos
doaj   +4 more sources

Cytogenetics, JAK2 and MPL mutations in polycythemia vera, primary myelofibrosis and essential thrombocythemia [PDF]

Revista Brasileira de Hematologia e Hemoterapia, 2011
BACKGROUND: The detection of molecular and cytogenetic alterations is important for the diagnosis, prognosis and classification of myeloproliferative neoplasms. OBJECTIVE: The aim of this study was to detect the following mutations: JAK2 V617F, JAK2 exon
Leonardo Caires dos Santos, Juliana Corrêa da Costa Ribeiro, Neusa Pereira Silva, Janete Cerutti, Maria Regina Regis da Silva, Maria de Lourdes Lopes Ferrari Chauffaille   +5 more
doaj   +2 more sources

ADVANCED THERAPY IN PATIENTS WITH PRIMARY AND POSTPOLYCYTHEMIC MYELOFIBROSIS [PDF]

Acta Biomedica Scientifica, 2017
Ph-negative myeloproliferative neoplasm are the group of hematologic disorders which includes primary myelofibrosis, polycythemia vera, essential trombocytemia and several rare diseases.
A. N. Alekseeva, O. E. Ochirova, L. B. Sodnomova, E. B. Zhalsanova   +3 more
doaj   +2 more sources

Primary Myelofibrosis

This chapter includes answers to practice‐based questions covering the new principles of diagnosis, treatment, and outcomes in Primary Myelofibrosis (PMF).
Venugopal, Sangeetha, Mascarenhas, John, Mesa, Ruben, Tremblay, Douglas   +3 more
core   +3 more sources

Primary autoimmune myelofibrosis: a report of three cases and review of the literature [PDF]

Turkish Journal of Hematology, 2009
Myelofibrosis in association with autoimmune disorders has been consistently recognized in sporadic case reports over a number of years. Autoimmune myelofibrosis has been described most commonly in association with systemic lupus erythematosus (SLE).
Rakhee Kar, Shyamali Dutta, Seema Tyagi
doaj   +1 more source

Primary Myelofibrosis [PDF]

, 2020
Abstract Myelofibrosis is a reactive process common to many malignant and benign disorders. Primary myelofibrosis is a chronic myeloproliferative neoplasm arising in a pluripotent haematopoietic stem cell. It results in abnormalities in red cell, granulocyte, and platelet production in association with marrow fibrosis and ...
Carmelo J. Blanquicett, Andrew Kuykendall   +1 more
  +6 more sources

Papel de la activación leucocitaria y plaquetaria en la trombosis de los síndromes mieloproliferativos crónicos [PDF]

, 2008
[spa] INTRODUCCIÓN Y OBJETIVOS: La causa fundamental de la trombosis en la policitemia vera y la trombocitemia esencial es el aumento de la viscosidad sanguínea secundaria a la eritrocitosis así como el incremento del número de plaquetas y las ...
Álvarez Larrán, Alberto
core   +6 more sources