Results 101 to 110 of about 1,216,395 (330)

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li   +12 more
wiley   +1 more source

Implementing a novel strategy for interprofessional medication review using collegial mentoring and systematic clinical evaluation in nursing homes (COSMOS)

open access: yesBMC Geriatrics, 2019
Background Multimorbid patients in nursing homes are prescribed long lists of medication, often without sufficient clinical evaluations beforehand.
Christine Gulla   +3 more
doaj   +1 more source

Patient-related effects of primary nursing : Protocol of a pilot randomized controlled trial. [PDF]

open access: yesMed Klin Intensivmed Notfmed, 2023
Krüger L   +7 more
europepmc   +1 more source

Omahoitajuus oikeuspsykiatrisen sairaalan kuntoutusosastolla : Potilaiden kokemuksia [PDF]

open access: yes, 2018
Opinnäytetyön tarkoituksena oli kuvailla suljetun kuntoutusosaston potilaiden kokemuksia omahoitajuudesta oikeuspsykiatrisessa sairaalassa. Tutkimuksen tavoitteena oli tuottaa kokemusperäistä tietoa omahoitajuuden toteutumisesta hoidon aikana potilaiden ...
Kujanpää, Kaisa, Pohjola, Eetu
core  

Label‐Free Leukocyte Biophysical Profiling Using Impedance‐Deformability Cytometry for Rapid Cardiovascular Risk Stratification

open access: yesAdvanced Science, EarlyView.
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He   +13 more
wiley   +1 more source

Home-based management of hypoxaemic COVID-19 patients: design of the Therapy@Home pilot study

open access: yesBMJ Open
Introduction During the COVID-19 pandemic, hospital capacity was strained. Home-based care could relieve the hospital care system and improve patient well-being if safely organised.We designed an intervention embedded in a regional collaborative ...
Frans H Rutten   +10 more
doaj   +1 more source

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy