Results 71 to 80 of about 91,310 (286)

Addition of Phentermine‐Topiramate to a Digitally Enhanced Lifestyle Intervention: A Double‐Blind Randomized Clinical Trial

Obesity, EarlyView.
ABSTRACT Objective This study compared the effects of phentermine‐topiramate‐ER (mid‐dose 7.5/46 mg) versus placebo on weight loss and cardiovascular disease (CVD) risk outcomes when used as an adjunct to a digitally enhanced lifestyle intervention (DELI).
Alejandro Campos, Wissam Ghusn, Lizeth Cifuentes, Daniel Sacoto, Sima Fansa, Diego Anazco, Maria L. Ricardo‐Silgado, Anas Hashem, Megan Schaefer, William S. Harmsen, Heather J. Gunn, Craig Peterson, Deborah Larsen, Santosh T. Varghese, Maria D. Hurtado, Andres Acosta   +15 more
wiley   +1 more source

Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility [PDF]

, 2017
Glaucoma is a multi-factorial blinding disease in which genetic factors play an important role. Elevated intraocular pressure is a highly heritable risk factor for primary open angle glaucoma and currently the only target for glaucoma therapy.
Allingham, R. (Rand), Aung, T. (Tin), Bailey, J.N.C. (Jessica N. Cooke), Bonnemaijer, P. (Peter), Brilliant, M.H. (Murray H.), Budenz, D.L. (Donald L.), Cheng, C.-Y. (Cheng-Yu), Chintalapudi, S.R. (Sumana R.), Chuen Khor, C. (Chiea), Craig, J.E. (Jamie), Di Wang, X. (Xiang), Duijn, C.M. (Cornelia) van, Fingert, J. (John), Gaasterland, D. (Douglas), Gaasterland, T. (Terry), Gharahkhani, P. (Puya), Haines, J.L. (Jonathan), Hammond, C.J. (Christopher J.), Hark, L. (Lisa), Hauser, M.A. (Michael), Hee Kang, J. (Jae), Hewitt, A. (Alex), Hoehn, R. (Rene), Hysi, P.G. (Pirro), Iglesias Gonzalez, A. (Adriana), Igo Jr., R.P. (Robert), Jablonski, M.M. (Monica M.), Jonansson, F. (Fridbert), Khawaja, A.P. (Anthony), Klaver, C.C.W. (Caroline), Kraft, P. (Peter), Lee, R.K. (Richard K.), Lichter, P.A. (Paul A.), Liu, Y. (Yutao), Lotery, A.J. (Andrew), MacGregor, S. (Stuart), Mackey, D.A. (David), Maria, D. (Doaa), Moroi, S. (Syoko), Pang, C. (Calvin), Pasquale, L.R. (Louis), Pasutto, F. (Francesca), Pericak-Vance, M.A. (Margaret), Realini, A. (Anthony), Rhee, D. (Doug), Richards, J.R. (Julia R.), Ritch, R. (Robert), Schuman, J.S. (Joel S.), Scott, W.K. (William), Singh, K. (Kuldev), Sit, A.J. (Arthur J.), Thorleifsson, G. (Gudmar), Thorsteinsdottir, U. (Unnar), Vitart, V. (Veronique), Vithana, E.N. (Eranga), Vollrath, D. (Douglas), Wiggs, J.L. (Janey L.), Williams, R.W. (Robert W.), Wollstein, G. (Gadi), Young, T.L. (Terri L.), Zack, D.J. (Donald), Zeller, T. (Tanja), Zwart, J-A. (John-Anker)   +62 more
core   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Success Rate of Trabeculectomy in Primary Glaucoma at Cicendo Eye Hospital on January–December 2013

Althea Medical Journal, 2016
Background: Trabeculectomy is a surgical therapy for glaucoma to preserve visual function by lowering intraocular pressure (IOP). In some studies, the success of trabeculectomy in lowering IOP is greater than medication. Success is defined by IOP
Erva Monica Saputro, Maula Rifada, RB. Soeherman Herdiningrat   +2 more
doaj   +1 more source

Filomicelle‐Embedded Composite Hydrogels for Localized Gelation Within the Anterior Chamber of the Eye

Small, EarlyView.
A composite hydrogel (C‐gel) incorporating PEG‐b‐PPS filomicelles enables localized in situ gelation and sustained nanocarrier release within the anterior chamber. The filamentous structure promotes spatial confinement of multi‐arm polymer crosslinking, even upon injection into large aqueous volumes, and gradually transitions into spherical micelles ...
Hyeohn Kim, Sofia Lara Ochoa, Swagat Sharma, Asmaa A. Youssif, Benjamin R Thomson, Mark Johnson, Evan A. Scott   +6 more
wiley   +1 more source

A study of primary open angle glaucoma in Diabetic patients [PDF]

Perspectives In Medical Research, 2018
Introduction: Primary open angle glaucoma is the commonest form of glaucoma accounting for atleast half of all the glaucomas. Intra Ocular Pressure is a definite and important risk factor for developing glaucomatous damage. Open-angle glaucoma is an
Shri Krishna Ingle1 , Yasam Soumya2 , Jaganmohan Rao3 , S. Kapil4
doaj  

A Randomised Open Label Comparative Clinical Trial on the Efficacy of Latanoprost and Timolol in Primary Open Angle Glaucoma [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Timolol, a beta blocker, is the most commonly prescribed first line therapy in the treatment of primary open angle glaucoma. Latanoprost, a prostaglandin analogue, is a novel drug in glaucoma therapy.
Sharadashri Rao, P.V. Narayanan
doaj   +1 more source

Explosive Weapons Trauma Care Collective (EXTRACCT) Blast Injury Clinical Practice Guideline: Ocular Trauma

World Journal of Surgery, EarlyView.
This clinical practice guideline from the Explosive Weapons Trauma Care Collective (EXTRACCT) group reviews current best practice for the management of ocular trauma in conflict‐affected regions, where explosive weapons are used and healthcare infrastructure is limited.
Emma Butterfield, Alistair Bolt, Gerry Clare, John Mattia, Aung Maw Tin‐U, Iddi Ndyabawe, Larry Schwab, Siegfried Karl Wagner, On behalf of the EXTRACCT Clinical Practice Guidelines Collaboration   +8 more
wiley   +1 more source

The medical management of glaucoma

South African Family Practice, 2017
Glaucoma is one of the leading causes of blindness worldwide. The main characteristic features include optic disc cupping, visual field loss, and in most instances a raised intraocular pressure.
André Marais, Elzbieta Osuch
doaj   +1 more source

Vascular risk factors in primary open angle glaucoma [PDF]

, 2004
To determine whether cardiovascular risk factors distribution differ between primary open-angle glaucoma (POAG) and control subjects. To assess the strength of this association in POAG.
Belzunce, A. (Arnaldo), Casellas, M. (M.)   +1 more
core