Central Corneal Thickness Comparison between Primary Open-Angle Glaucoma Patients and Healthy Controls [PDF]
Glaucoma is a progressive eye disease characterized by optic nerve damage and visual field loss, often associated with elevated intraocular pressure (IOP).
Alsagheer, Hanan +2 more
core +2 more sources
Circumpapillary OCT-Focused Hybrid Learning for Glaucoma Grading Using Tailored Prototypical Neural Networks [PDF]
arXiv, 2021 Glaucoma is one of the leading causes of blindness worldwide and Optical Coherence Tomography (OCT) is the quintessential imaging technique for its detection. Unlike most of the state-of-the-art studies focused on glaucoma detection, in this paper, we propose, for the first time, a novel framework for glaucoma grading using raw circumpapillary B-scans.
arxiv
Fluorescence Lifetime Imaging Techniques—A Review on Principles, Applications and Clinical Relevance
Journal of Biophotonics, EarlyView.This article gives an overview of the most frequently used fluorescence‐lifetime imaging (FLIM) techniques, their capabilities and typical applications in biology and clinical studies. ABSTRACT This article gives an overview of the most frequently used fluorescence‐lifetime imaging (FLIM) techniques, their capabilities, and typical applications ...
V. I. Shcheslavskiy +5 more
wiley +1 more source
Primary open-angle glaucoma genes [PDF]
Eye, 2011 A substantial fraction of glaucoma has a genetic basis. About 5% of primary open angle glaucoma (POAG) is currently attributed to single-gene or Mendelian forms of glaucoma (ie glaucoma caused by mutations in myocilin or optineurin). Mutations in these genes have a high likelihood of leading to glaucoma and are rarely seen in normal subjects.
openaire +3 more sources
Harvard Glaucoma Detection and Progression: A Multimodal Multitask Dataset and Generalization-Reinforced Semi-Supervised Learning [PDF]
arXiv, 2023 Glaucoma is the number one cause of irreversible blindness globally. A major challenge for accurate glaucoma detection and progression forecasting is the bottleneck of limited labeled patients with the state-of-the-art (SOTA) 3D retinal imaging data of optical coherence tomography (OCT).
arxiv
Apoptosis in the trabecular meshwork of glaucomatous patients [PDF]
, 2008 We established and validated an in toto method to perform TdT-mediated dUTP nick end labeling to study apoptosis in human trabecular meshwork tissue obtained during trabeculectomy in glaucoma patients.
Baleriola, Jimena +5 more
core +1 more source
Can tight necktie be a risk factor in development and progression of primary- Open Angle Glaucoma (POAG)? [PDF]
, 2011 Tight neckties have been documented to alter intraocular pressure (IOP) and thus may be a risk factor in the development and progression of primary open angle glaucoma (POAG).
Ajayi, OB, Akinlabi, AG, Akporobaro, N
core +2 more sources
Preclinical Testing of 3D Printed, Cell Loaded Hydrogel Based Corneal Substitutes on Rabbit Model
Macromolecular Bioscience, EarlyView.This study reports on 3D‐printed methacrylated gelatin (GelMA) implants designed to serve as corneal stroma substitutes. The implants are characterized for their transparency, mechanical strength, and cytocompatibility. In vivo tests on rabbits demonstrate successful integration, with histopathological analysis showing tissue regeneration, appropriate ...
Deniz Basoz +6 more
wiley +1 more source
Robust Segmentation of Optic Disc and Cup from Fundus Images Using Deep Neural Networks [PDF]
arXiv, 2020 Optic disc (OD) and optic cup (OC) are regions of prominent clinical interest in a retinal fundus image. They are the primary indicators of a glaucomatous condition. With the advent and success of deep learning for healthcare research, several approaches have been proposed for the segmentation of important features in retinal fundus images.
arxiv
DNA sequence variants in the LOXL1 gene are associated with pseudoexfoliation glaucoma in a U.S. clinic-based population with broad ethnic diversity [PDF]
, 2008 Background Pseudoexfoliation syndrome is a major risk factor for glaucoma in many populations throughout the world. Using a U.S. clinic-based case control sample with broad ethnic diversity, we show that three common SNPs in LOXL1 previously associated ...
B Nemesure +48 more
core +3 more sources