Results 131 to 140 of about 66,541 (257)

Advancing Treatment of Degenerative Eye Diseases at the Nanoscale

Smart Medicine, Volume 5, Issue 4, August 2026.
Nanotherapeutics possess the potential to overcome longstanding bottlenecks in treating degenerative ophthalmic diseases. With a highly tunable surface chemistry, nanotechnology platforms can be customized to navigate specific anatomical barriers in the eye and target pathways of diseases.
Li Yao Jin, Evashiniee G. P. Selvam, Qinsong Mei, Chi D. Luu, Yeannie H. Y. Yap, Daniel B. L. Teh   +5 more
wiley   +1 more source

THE ROLE OF THE LOCAL AND GENERAL SOMATIC FACTORS FOR THE OPEN-ANGLE GLAUCOMA DEVELOPMENT IN PATIENTS WITH EYE MANIFESTATIONS OF PSEUDOEXFOLIATION SYNDROME

Офтальмохирургия, 2015
Pseudoexfoliation syndrome (PES) is one of the best known triggers of glaucoma. The development of the open-angle glaucoma only in some patients with the PES with definite local and general risk factors requires a further research.Purpose.
V. V. Agafonova, M. Z. Frankovska-Gerlak, T. V. Sokolovskaya, P. E. Brizhak, A. N. Bessarabov   +4 more
doaj  

Microenvironment‐Responsive Drug Delivery Systems for Ocular Surface Diseases: Mechanisms, Applications, and Translational Challenges

Small Science, Volume 6, Issue 8, August 2026.
Microenvironment‐responsive drug delivery systems overcome ocular physiological barriers by responding to temperature, pH, ions, reactive oxygen species, and enzymes. This review bridges material design, performance evaluation, and clinical translation, offering actionable insights for treating dry eye disease, infectious keratitis, and corneal ...
Jiamin Liu, Liangbo Chen, Yao Fu, Siyi Zhang   +3 more
wiley   +1 more source

The role of the local and general somatic factors for the open-angle glaucoma development in patients with eye manifestations of pseudoexfoliation syndrome

Офтальмохирургия, 2013
Pseudoexfoliation syndrome (PEX) is one of the best known triggers of glaucoma. The development of the open-angle glaucoma only in some patients with the PEX with definite local and general risk factors requires a further research. Purpose.
V.V. Agafonova,, M.Z. Frankovska-Gerlak, T.V. Sokolovskaya, P.E. Brizhak,, A.N. Bessarabov   +4 more
doaj  

Proteomic and metabolic signatures of female reproductive factors and risk of age‐related ocular diseases: A large prospective cohort study

VIEW, Volume 7, Issue 4, August 2026.
The full editable vector source file of this graphical abstract is uploaded as a supplementary EPS file for typesetting. All elements are copyright‐free. Abstract Age‐related ocular diseases (ARODs), including cataract, primary open‐angle glaucoma (POAG), and age‐related macular degeneration (AMD), are leading causes of vision impairment and exhibit ...
Linge Jian, Zhiqian Huang, Keke Zhang, Jing Lin, Jia You, Yi Lu, Xiangjia Zhu   +6 more
wiley   +1 more source

Retinal oxygen saturation and retinal vessel diameter in glaucoma patients before and after trabeculectomy

Acta Ophthalmologica, Volume 104, Issue 5, Page 544-550, August 2026.
Abstract Purpose To compare retinal vessel oxygen saturations and diameters before, 1 and 3 months after trabeculectomy. Methods Retinal oxygen saturations and vessel diameters were obtained using retinal oximetry. The effect of the postoperative intraocular pressure (IOP) decrease on the arteriovenous difference (AV‐difference) was evaluated ...
S. Kemp, A. Ahmadzadeh, B. Schmidt, O. N. Klefter, L. Kessel, D. Bach‐Holm   +5 more
wiley   +1 more source

Prognostic factors of optical coherence tomography angiography in intermediate and advanced primary open‐angle glaucoma: A systematic review and meta‐analysis

Acta Ophthalmologica, Volume 104, Issue 5, Page e491-e502, August 2026.
Abstract Conventional optical coherence tomography (OCT) has a floor effect in patients with severe visual field loss, such as seen in advanced primary open‐angle glaucoma (POAG). OCT angiography (OCTA) does not suffer from such a floor effect. However, which OCTA parameters are most useful for monitoring longitudinal progression is unclear.
Kamya Katarya, Victor A. de Vries, João Barbosa‐Breda, Luisa Sanchez Brea, Danilo Andrade De Jesus, Wishal D. Ramdas   +5 more
wiley   +1 more source

Aqueous humor level of sCD44 in patients with degenerative myopia and primary open-angle glaucoma

BMC Research Notes, 2009
Background The transmembrane glycoprotein CD44 is a major hyaluronan cell surface receptor widely distributed in eye tissues and fluids. The shed ectodomain of CD44 is termed soluble CD44 and is toxic to human retinal ganglion cells in cell culture.
Akdogan Muberra, Budak Yasemin U, Huysal Kagan   +2 more
doaj  

Impact of mono‐ or multitherapy on ocular surface health and quality of life after 5 years of follow‐up in the Glaucoma Intensive Treatment Study (GITS)

Acta Ophthalmologica, Volume 104, Issue 5, Page 535-543, August 2026.
Abstract Aim To evaluate the impact of initial mono‐ versus multitherapy on the ocular surface and related quality of life after 5 years follow‐up in the Glaucoma Intensive Treatment Study (GITS). Method The study included patients with primary open‐angle glaucoma and pseudoexfoliation glaucoma who completed 5‐year follow‐up in GITS.
Gauti Jóhannesson, Christina Lindén, Johan Aspberg, Sabina Andersson‐Geimer, Anders Heijl, Boel Bengtsson, Dorothea Peters   +6 more
wiley   +1 more source

Astigmatic changes after Descemet membrane endothelial keratoplasty (DMEK) in decompensated penetrating keratoplasty grafts

Acta Ophthalmologica, Volume 104, Issue 5, Page e516-e529, August 2026.
Abstract Purpose To evaluate the surgery‐induced changes of astigmatism after Descemet membrane endothelial keratoplasty (DMEK) in eyes with failed previous penetrating keratoplasty (PK). Design Retrospective, interventional cohort study based on prospective DMEK database.
Florian Thomas Steinberg, Jithmi Weliwitage, Marie von Berg, Silvia Schrittenlocher, Simona Schlereth, Claus Cursiefen, Björn Bachmann   +6 more
wiley   +1 more source