Results 211 to 220 of about 36,695 (249)

Genetics of primary open angle glaucoma

Japanese Journal of Ophthalmology, 2013
Glaucoma is a neurodegenerative disease and one of the leading causes of irreversible blindness, affecting over 60 million people worldwide. At the present time, glaucoma is clinically defined, but the exact etiology is unknown. Genetic studies are one approach to identify the molecules and pathways involved in disease pathogenesis.
Mitsuko, Takamoto, Makoto, Araie
openaire   +2 more sources

Optineurin in primary open angle glaucoma

Ophthalmology Clinics of North America, 2003
The authors' initial estimate indicated that mutations in Optineurin are responsible for a significant proportion of LPG/POAG families. Currently, there are up to 1.2 million persons with LPG and up to 2.47 million persons with POAG in the United States alone.
Mansoor, Sarfarazi, Tayebeh, Rezaie
openaire   +2 more sources

Primary Open-Angle Glaucoma

Journal of Gerontological Nursing, 2011
Glaucoma is an optic neuropathy that is usually associated with an elevated intraocular pressure. Primary open-angle glaucoma (POAG) is the most common type of glaucoma and is progressive and bilateral but typically asymmetric in patients. Studies have shown that reducing intraocular pressure reduces the risk of vision loss.
Jasmine W, Yumori, Mary P, Cadogan
openaire   +2 more sources

Heredity in primary open-angle glaucoma

Current Opinion in Ophthalmology, 2000
The past years have seen considerable progress in the characterization of hereditary factors in primary open-angle glaucoma. Epidemiologic studies strengthened our knowledge of the hereditary factors in this multifactorial disease. Several loci in the human genome have been described, which segregate with different glaucoma phenotypes. Mutations of the
openaire   +2 more sources

Mortality in Primary Open-Angle Glaucoma and Exfoliative Glaucoma

European Journal of Ophthalmology, 2014
Purpose To study mortality among unselected Finnish patients with either primary open-angle glaucoma (POAG) or exfoliative glaucoma (EG) after a minimum follow-up of 7 years after enrollment. Methods A total of 344 patients with POAG ...
Tarkkanen Ahti H. A., Kivela Tero T., Tarkkanen Ahti H. A., Kivela Tero T.   +3 more
openaire   +2 more sources

Goniodysgenesis in familial primary open‐angle glaucoma

Acta Ophthalmologica, 1994
Abstract. Results of a pilot study to evaluate goniodysge‐nesis as a cause of familial open‐angle glaucoma are reported. Patients with a familial high tension open‐angle glaucoma and a goniodysgenetic chamber angle (n = 11), a number of their relatives with glaucoma (n = 12), and their relatives without glaucoma (n = 26) were compared to a group of ...
Verbraak, F. D., vd Berg, W., Delleman, J. W., Greve, E. L.   +3 more
openaire   +3 more sources

Pathogenesis of primary open‐angle glaucoma

Clinical & Experimental Ophthalmology, 2012
Editorial ; Robert J ...
openaire   +3 more sources

The management of primary open angle glaucoma

Drug and Therapeutics Bulletin, 1997
Glaucoma is one of the commonest causes of blindness in the world.1 In the UK, about 7% of people over the age of 75 years have primary open angle glaucoma, the most common type of glaucoma2 and the cause of visual impairment in about 13% of those registered blind.3,4 Early detection and treatment can usually prevent blindness.5 However, half of all ...
openaire   +2 more sources

Primary Open Angle Glaucoma

2013
Primary open-angle glaucoma is a hereditary disease which alters the evacuation of aqueous humor, in the trabecular area. This alteration causes an increase in the intraocular pressure at pathological rates, which after some time causes anatomical damage to the optic nerve and functional damage to the visual field: characteristic of glaucoma.
Roberto Sampaolesi, Juan Roberto Sampaolesi, Jorge Zárate   +2 more
openaire   +1 more source

Diagnosis of Primary Open-Angle Glaucoma

JAMA, 2013
Jinhai, Huang, Giacomo, Savini, Qinmei, Wang   +2 more
openaire   +2 more sources