BRAF inhibitors and MEK inhibitors (MEKi) have reshaped the treatment of BRAFV600‐mutant malignancies; however, cutaneous adverse drug reactions (ADRs) remain a frequent and clinically impactful toxicity. Although clinical trials provide insight into their safety profiles, real‐world data on dermatologic ADRs are limited.
Natalia Sauer +3 more
wiley +1 more source
Single port thoracoscopic sympathectomy for primary palmar hyperhidrosis in adolescence
Hyperhidrosis is defined as excessive sweating beyond the physiologic needs of a person. Palmar hyperhidrosis in the adolescent period may have an impact on school work and may cause psychological problems. In this study we aim to increase awareness of this disregarded problem.We explicated the early outcomes of 7 consecutive adolescents, where single ...
Gunal, Nesimi +3 more
openaire +3 more sources
Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
Development and Validation of the Japanese Version of the Hyperhidrosis Quality of Life Index
ABSTRACT Hyperhidrosis decreases an individual's quality of life (QOL). The Hyperhidrosis Quality of Life Index (HidroQoL) measures the impact of hyperhidrosis on QOL and has established reliability and validity. However, a Japanese version does not exist.
Sayaka Ogawa +7 more
wiley +1 more source
Excited Skin Syndrome (Angry Back), What Do We Know About It? A Review of the Literature
ABSTRACT Background In 1975, Mitchell brought up a theory that false positive reactions can be due to skin hyperirritability, called it “angry back syndrome” (ABS). The phenomenon is observed in patch testing of patients with several positive patch tests, mostly along with one or more strong reactions.
Amir Mohammad Beyzaee, Howard I. Maibach
wiley +1 more source
Long-Term Impact of Endoscopic Thoracic Sympathectomy for Primary Palmar Hyperhidrosis [PDF]
Endoscopic thoracic sympathectomy (ETS) is the gold standard treatment for primary hyperhidrosis, with excellent short-term results. The potential for adverse effects, particularly compensatory sweating (CS), may affect long-term satisfaction. In this retrospective review we aimed to examine long-term results and quality of life (QOL) after ETS in the ...
Leah C, Horslen +3 more
openaire +2 more sources
Intradermal Botulinum Neurotoxin Injection Versus Thoracoscopic Sympathectomy in Pediatric Patients With Primary Palmar Hyperhidrosis (Comparative Study) [PDF]
Background: Botulinum neurotoxins are injected intradermally into the palm to normalize sweating, its effect appears 48e72 h after injection, and it can be repeated within 2 weeks after the first injection as a booster dose.
Abd El Rahman Awadeen Abd El Rahman +3 more
doaj +1 more source
ABSTRACT Primary hypertrophic osteoarthropathy (Pachydermoperiostosis) is a rare, inherited genetic disorder of the skeleton and the skin, characterised by clubbing of the fingers, thickening of the skin especially of the face and forehead (pachydermia) and periostosis. Patients often present with pain and swelling of the knees and ankles.
Ahmed AbdulBari +3 more
wiley +1 more source
Impact of Thoracoscopic T2 Sympathectomy on Patients With Primary Palmar and Axillary Hyperhidrosis [PDF]
There are different techniques for thoracoscopic sympathectomy for management of primary hyperhidrosis. Each technique has the advantage of giving good surgical results, but may cause complications, which depend on the level of sympathectomy used in each technique.From October 2012 to August 2016, a total number of 120 patients (of primary palmar and ...
Ehab F, Salim, Gaser A, Ali
openaire +2 more sources
Outcome of radiofrequency sympathectomy in palmar hyperhidrosis
Background Hyperhidrosis is a pathological condition characterized by excessive sweating, regardless of thermoregulatory needs, due to primary or secondary causes.
Mohammud Ahmud Salim +4 more
doaj +1 more source

