Results 191 to 200 of about 5,857,342 (337)

A multicentre analysis of efficacy, safety and molecular response correlates of fostamatinib in warm autoimmune haemolytic anaemia and Evans syndrome

open access: yesBritish Journal of Haematology, EarlyView.
Fostamatinib had 46% durable response, with 73% steroid reduction, in this multicentre retrospective study of refractory wAIHA/ES. Hypertension, gastrointestinal (GI) distress and neutropenia occurred in 23%. Only one patient required drug discontinuation and one patient dose reduction.
Jorge N. Ruiz Lopez   +16 more
wiley   +1 more source

Effectiveness of Glucocorticoids in the No-Reflow Phenomenon in STEMI Patients

open access: yesУкраїнський журнал серцево-судинної хірургії
Relevance. The driving force behind the pathogenesis of no-reflow, as a component of ischemic-reperfusion injury, is myocardial edema, which provokes extravascular compression of the infarct-related artery (IRA), making it impossible to restore antegrade
Maksim Y. Sokolov   +3 more
doaj  

GLP‐1 Receptor Agonist Therapy and Cardiorenal Outcomes in Type 1 Diabetes: A Propensity‐Matched Real‐World Analysis

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Evidence on cardiovascular/renal outcomes associated with GLP‐1‐based therapies in type 1 diabetes (T1D) is limited. We examined the effects of GLP‐1‐based therapy on major clinical outcomes and safety, including diabetic ketoacidosis (DKA) and hypoglycemia risk, in adults with T1D in a large real‐world cohort.
Anastasios Tentolouris   +7 more
wiley   +1 more source

Eroded Versus Ruptured Plaques at the Culprit Site of STEMI: In Vivo Pathophysiological Features and Response to Primary PCI.

open access: yesJACC Cardiovascular Imaging, 2015
F. Saia   +16 more
semanticscholar   +1 more source

Oxygen‐independent expression of HIF‐1α during the cell cycle in hepatocellular carcinoma cells controls essential metabolic pathways under normoxia

open access: yesThe FEBS Journal, EarlyView.
In Huh7 cells, HIF‐1α is essential as it maintains the expression of proteins involved in glycolysis and steroid/cholesterol biosynthesis both under normoxia and hypoxia. On the other hand, in HeLa cells, these pathways are induced by HIF‐1α only under hypoxia.
Ioanna‐Maria Gkotinakou   +6 more
wiley   +1 more source

Myocardial Damage After Primary PCI

open access: yesJACC: Cardiovascular Interventions, 2020
Sebastian Johannes Reinstadler   +1 more
openaire   +1 more source

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