Results 31 to 40 of about 172,679 (280)

Myocardial reperfusion injury: looking beyond primary PCI [PDF]

European Heart Journal, 2013
Coronary heart disease (CHD) is the leading cause of death and disability in Europe. For patients presenting with an acute ST-segment elevation myocardial infarction (STEMI), timely myocardial reperfusion using either thrombolytic therapy or primary percutaneous coronary intervention (PPCI) is the most effective therapy for limiting myocardial infarct (
Fröhlich Georg M, Meier Pascal, White Steven K, Yellon Derek M, Hausenloy Derek J   +4 more
openaire   +2 more sources

Primary PCI versus pharmacoinvasive strategy for ST elevation myocardial infarction

International Journal of Cardiology: Heart & Vasculature, 2018
Background: The rationale for pharmacoinvasive strategy is that many patients have a persistent reduction in flow in the infarct-related artery.
Ayman M. Helal, Sameh M. Shaheen, Walid A. Elhammady, Mohamed I. Ahmed, Ahmed S. Abdel-Hakim, Lamyaa E. Allam   +5 more
doaj   +1 more source

A comparison of rescue and primary percutaneous coronary interventions for acute ST elevation myocardial infarction

Indian Heart Journal, 2017
Objective: To perform a comparative analysis of in-hospital results obtained from patients with acute ST elevation myocardial infarction (STEMI), who underwent rescue or primary percutaneous coronary intervention (PCI). The aim is to determine rescue PCI
M.B. Faslur Rahuman, Jayanthimala B. Jayawardena, George R. Francis, Niraj Mahboob, Wasantha Kumara A.H.T., Aruna Wijesinghe, Rashan Haniffa, Ranithrie Ariyapperuma, Abbyramy Paramanayakam, Pubudu A. De Silva   +9 more
doaj   +1 more source

Identification of Bruton's tyrosine kinase as a therapeutic target in acute myeloid leukemia [PDF]

, 2014
Bruton's tyrosine kinase (BTK) is a cytoplasmic protein found in all hematopoietic cell lineages except for T cells. BTK mediates signalling downstream of a number of receptors.
Advani, Alam, Ashino, Baba, Bendall, Billottet, Burger, Burger, Byrd, Chang, Cordle, Dasmahapatra, David J. MacEwan, de Weers, Dos Santos, Doyle, Fiedler, Gallay, Grandage, Gu, Guzman, Hahn, Herman, Herrmann, Honda, Honigberg, Horwood, Ishii, Juliusson, Kawakami, Kim, Kojima, Kristian M. Bowles, Kvinlaug, Lyubov Zaitseva, Megan Y. Murray, Min, Mohamed, Nanri, Park, Quek, Renneville, Rushworth, Rushworth, Rushworth, Shinners, Sivina, Spiekermann, Stuart A. Rushworth, Sujobert, Tai, Tamburini, Tomasson, Tsukada, Vellenga, Venkataraman, Vetrie, Welch, Westermann, Zaitseva   +59 more
core   +1 more source

Left ventricular global longitudinal strain following revascularization in acute ST elevation myocardial infarction – A comparison of primary angioplasty and Streptokinase-based pharmacoinvasive strategy

Indian Heart Journal, 2017
Objective: Tenecteplase-based pharmacoinvasive percutaneous coronary intervention (PCI) has been shown to yield outcomes comparable to primary PCI in the setting of acute ST elevation myocardial infarction (STEMI).
Amal Paul, Paul V. George
doaj   +1 more source

Systematic review and meta-analysis of optimal P2Y₁₂ blockade in dual antiplatelet therapy for patients with diabetes with acute coronary syndrome [PDF]

, 2016
Background: Patients with diabetes are at increased risk of acute coronary syndromes (ACS) and their mortality and morbidity outcomes are significantly worse following ACS events, independent of other comorbidities.
Brown, Oliver I, Hoye, Angela, Rossington, Jennifer A   +2 more
core   +1 more source

Initiation and persistence with dual antiplatelet therapy after acute myocardial infarction:a Danish nationwide population-based cohort study [PDF]

, 2016
OBJECTIVES: The study investigated dual antiplatelet therapy (DAPT) patterns over time and patient characteristics associated with the various treatments in a myocardial infarction (MI) population.
Broe, Anne, Diness, Thomas Goldin, Emneus, Martha, Gislason, Gunnar H, Green, Anders, Hasvold, Pål, Pottegård, Anton   +6 more
core   +2 more sources

Staged versus One-Time Complete Revascularization with Percutaneous Coronary Intervention in STEMI Patients with Multivessel Disease: A Systematic Review and Meta-Analysis.

PLoS ONE, 2017
IntroductionIn patients with acute ST-elevation myocardial infarction (STEMI), the preferred intervention is percutaneous coronary intervention (PCI).Whether staged PCI (S-PCI) or one-time complete PCI (MV-PCI) is more beneficial and safer in terms of ...
Zhenwei Li, Yijiang Zhou, Qingqing Xu, Xiaomin Chen   +3 more
doaj   +1 more source

Percutaneous Coronary Intervention after Fibrinolysis for ST-Segment Elevation Myocardial Infarction Patients: An Updated Systematic Review and Meta-Analysis.

PLoS ONE, 2015
BackgroundPercutaneous coronary intervention (PCI), fibrinolysis and the combination of both methods are current therapeutic options for patients with ST-segment elevation myocardial infarction (STEMI).MethodsWe searched PubMed, EMBASE, Google scholar ...
Feng Liu, Qinglong Guo, Guoqiang Xie, Han Zhang, Yaxi Wu, Lixia Yang   +5 more
doaj   +1 more source

Fibrinolysis or Primary PCI in ST-Segment Elevation Myocardial Infarction [PDF]

, 2013
BACKGROUNDIt is not known whether prehospital fibrinolysis, coupled with timely coronary angiography, provides a clinical outcome similar to that with primary percutaneous coronary intervention (PCI) early after acute ST-segment elevation myocardial ...
Armstrong, Paul W., Arntz, Hans-Richard, Bluhmki, Erich, Bogaerts, Kris, Carvalho, Antonio C., Danays, Thierry, Fresco, Claudio, Gershlick, Anthony H., Goldstein, Patrick, Grajek, Stefan, Halvorsen, Sigrun, Huber, Kurt, Lambert, Yves, Nanas, John, Ostojic, Miodrag, Regelin, Anne, Rosell Ortiz, Fernando, STREAM Investigative Team, Sulimov, Vitaly, Van de Werf, Frans, Vandenberghe, Katleen, Welsh, Robert C., Wilcox, Robert   +22 more
core   +1 more source