Results 61 to 70 of about 76,007 (204)

Impact of CYP2C19 and CYP3A4 Inhibitor Use on Clopidogrel Clinical Effectiveness in CYP2C19 Genotyped Patients Undergoing Percutaneous Coronary Intervention

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 and CYP3A4 contribute to clopidogrel bioactivation. CYP2C19 no‐function alleles diminish clopidogrel's antiplatelet effects and clinical effectiveness. Coadministration of either a CYP2C19 or a CYP3A4 inhibitor may also reduce clopidogrel's antiplatelet effects and lead to phenoconversion in patients without a CYP2C19 no‐function allele (normal/
Danwei Shao, Jean G. Malavé, Joseph S. Rossi, Francesco Franchi, Ellen C. Keeley, Dominick J. Angiolillo, George A. Stouffer, Larisa H. Cavallari, Craig R. Lee   +8 more
wiley   +1 more source

CHA2DS2-VASc, a Simple Clinical Score Expanding Its Boundaries to Predict Contrast-Induced Acute Kidney Injury After Primary Percutaneous Coronary Interventions

International Journal of Nephrology and Renovascular Disease, 2021
Rajesh Kumar,1 Mahesh Kumar Batra,1 Sanam Khowaja,1 Ali Ammar,1 Ashok Kumar,1 Jehangir Ali Shah,1 Jawaid Akbar Sial,1 Tahir Saghir,1 Musa Karim2 1Adult Cardiology Department, National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan ...
Kumar R, Batra MK, Khowaja S, Ammar A, Kumar A, Shah JA, Sial JA, Saghir T, Karim M   +8 more
doaj  

Correlation of Admission Level of Galectin-3 and Cardiac Remodeling after Primary Percutaneous Coronary Intervention [PDF]

International Journal of Medical Arts
Background: Galectin-3, a biomarker associated with cardiac remodeling, has been linked to poor outcomes in patients with acute STEMI. Understanding its predictive capacity after primary percutaneous coronary intervention [PPCI] is critical for improving
Hussein Hassan, Mostafa Al-Sawasany, Ibrahim Said, Hani khalaf   +3 more
doaj   +1 more source

Bridging Theory and Prediction: A Hybrid SEM and Machine Learning Approach to Optimize Lean Construction for Megaproject Sustainability in China

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Construction megaprojects, large‐scale, complex, and capital‐intensive, are particularly prone to inefficiencies, cost overruns, delays, and environmental degradation due to fragmented workflows, stakeholder misalignment, and resource intensity.
Abdelazim Ibrahim, Tarek Zayed, Zoubeir Lafhaj, Ahmed Maged, Ahmed Farouk Kineber, Jingchao Yang   +5 more
wiley   +1 more source

SYNTAX residual in long-term outcomes prognosis of endovascular revascularization in myocardial infarction with ST elevation and multivessel disease

Кардиоваскулярная терапия и профилактика, 2016
Aim. To study prognostic significance of coronary atherosclerosisseverity (residual SYNTAX) after primary percutaneous intervention (PCI) in myocardial infarction patients with STE (STEMI) and multivessel coronary lesion, in long term period.Material and
R. S. Tarasov, V. I. Ganyukov, K. M. Vakkosov, O. L. Barbarash, L. S. Barbarash   +4 more
doaj   +1 more source

Thermal‐induced fracture evolution and acoustic signature of Beishan granite: Insights into tensile strength of barrier system for high‐level radioactive waste disposal

Deep Underground Science and Engineering, EarlyView.
The tensile strength of granite, a proposed host for nuclear waste, degrades severely above 400°C. We link this to specific microcracking patterns captured by acoustic emission, establishing a scientific basis for assessing repository safety under thermal load.
Wei Zeng, Shijie Li, Xiaozhao Li, Zhen Huang, Shangtong Yang, Wentao Xu, Biao Wang, Yun Wu   +7 more
wiley   +1 more source

SYNTAX scale estimates of coronary stenosis severity and outcomes of various revascularisation strategies in patients with ST segment elevation myocardial infarction and multi-vessel coronary pathology

Российский кардиологический журнал, 2013
Aim. To assess 30-day and long-term outcomes of various revascularisation strategies in patients with myocardial infarction and ST segment elevation (STEMI) and multi-vessel coronary pathology (MVCP), in regard to the severity of coronary stenosis, as ...
R. S. Tarasov, V. I. Ganyukov, P. A. Shushpannikov, P. A. Krotikov, O. L. Barbarash, L. S. Barbarash   +5 more
doaj   +1 more source

Uniaxial compressive strength prediction and ratio parameter optimization of titanium tailings composite backfill materials using intelligent hybrid models

Deep Underground Science and Engineering, EarlyView.
Based on the 90 datasets, ERT and four optimization algorithms were used to build four hybrid models to predict the UCS of the backfill body. The SMA‐ERT model was the most effective model, and it can reliably guide the design of the backfill ratio parameters. Abstract This study analyzed the feasibility of using titanium (Ti) tailings as a backfilling
Weijun Liu, Zida Liu, Zhixiang Liu
wiley   +1 more source

Predictive accuracy of systolic blood pressure to left ventricular end-diastolic pressure ratio versus TIMI score for short-term mortality after primary percutaneous coronary intervention [PDF]

Journal of Cardiovascular and Thoracic Research
Introduction: Aim of this study was to evaluate the predictive performance of systolic blood pressure (SBP) to left ventricular end-diastolic pressure (LVEDP) ratio for the prediction of in-hospital and short-term mortality in a contemporary cohort of ...
Rajesh Kumar, Naveed Ullah Khan, Ali Bin Naseer, Zille Huma, Kalsoom Chachar, Maryam Samad, Muhammad Ishaq, Abiha Urooj, Uroosa Safdar, Muhammad Rasool, Sohail Khan, Jawaid Akbar Sial, Tahir Saghir, Nadeem Qamar   +13 more
doaj   +1 more source

Forecasting heart failure: Seasonal alignment of heart failure outcomes in New York

ESC Heart Failure, Volume 12, Issue 2, Page 819-831, April 2025.
Abstract Background Seasonal variations have been observed in heart failure (HF) hospitalization. Numerous explanatory mechanisms have been proposed, but no prior studies have examined potential contributors directly. Our objective was to identify specific factors that could contribute to seasonal variability using a large longitudinal dataset of HF ...
Prerna Gupta, Ellen Brinza, Prateeti Khazanie, Pamela N. Peterson, P Michael Ho, David P. Kao   +5 more
wiley   +1 more source