Results 171 to 180 of about 79,826 (246)

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2236-2255, May 2026.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi   +19 more
wiley   +1 more source

Association between diabetes and in‐hospital outcomes in patients with metabolic dysfunction‐associated steatotic liver disease hospitalized for cardiovascular disease: A nationwide database study

open access: yesDiabetic Medicine, Volume 43, Issue 5, May 2026.
In a nationwide cohort of 10,614 patients with metabolic dysfunction–associated steatotic liver disease (MASLD) hospitalized for cardiovascular disease (CVD), diabetes was present in 4550 patients (43%) and was independently associated with higher in‐hospital mortality and cardiovascular complications.
Soichi Komaki   +11 more
wiley   +1 more source

Management and Prognosis of Patients With Acute Pericarditis in the Emergency Department: A Retrospective, Single‐Centre Study

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
In this retrospective, single‐centre study conducted in patients with acute pericarditis referred to the Emergency Department, a significant proportion of patients experienced long‐term complications, especially recurrences. Drug doses were compliant with guidelines in a limited number of patients at admission and increased at discharge. Diabetes, COPD,
Lisa Caldera   +7 more
wiley   +1 more source

Prehospital Risk Stratification Using Unsupervised Machine Learning in STEMI

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
Machine learning identified three phenotypes with 30‐day mortality of 3.4%, 22.1%, and 75%. Phenotype‐2 reveals an "occult high‐risk" group: hemodynamically stable yet six‐fold higher mortality. ABSTRACT Background ST‐elevation myocardial infarction (STEMI) exhibits substantial clinical heterogeneity complicating prehospital risk stratification ...
Ana Ramos‐Rodríguez   +7 more
wiley   +1 more source

From Adipose Tissue to Cardiac Repair: Extracellular Vesicles in Cardiovascular Regeneration

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Adipose‐derived extracellular vesicles (ADEVs) secreted by adipose tissue have gained increasing attention due to their regenerative and immunomodulatory properties in cardiovascular diseases. They carry proteins, lipids, and nucleic acids that mediate intercellular communication and influence cardiac pathophysiology. In atherosclerosis, ADEVs
Karolina Ignaczak   +6 more
wiley   +1 more source

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