Quality indicators for lifestyle or behavioural management for the primary prevention of cardiovascular disease in primary care: a systematic review. [PDF]
Bam K +10 more
europepmc +1 more source
Construction of educational material for child overweight prevention in primary health care
Mirna Ferré Fontão Más
openalex +1 more source
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Identification and management of patients at high-risk for cardiovascular disease in primary prevention. [PDF]
Ahlers M +4 more
europepmc +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
The Timing for Primary Prevention for ICD in the Current Era of Pharmacotherapy. [PDF]
Shchendrygina A, Yehya A, Skouri H.
europepmc +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Genetic Risk Score Enables a Vaccine for Early Primary Prevention of CAD. [PDF]
Roberts R.
europepmc +1 more source
Evaluation of low-dose aspirin for primary prevention of ischemic stroke among patients with diabetes: a retrospective cohort study [PDF]
Ye‐Jee Kim +9 more
openalex +1 more source

