Results 201 to 210 of about 7,735,427 (345)

Moving primary prevention into a tertiary care hospital? [PDF]

open access: yesEnviron Health Prev Med
Geindreau D   +5 more
europepmc   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

open access: yesFEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro   +8 more
wiley   +1 more source

Sex Differences in Cardiovascular Health Status and Long-Term Outcomes in a Primary Prevention Cohort. [PDF]

open access: yesJACC Adv
Sud M   +12 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

Cholesterol Levels and Cardiovascular Outcomes Following Statin Initiation for Primary Prevention: A Cohort Study. [PDF]

open access: yesJACC Adv
Thompson W   +14 more
europepmc   +1 more source

Enhancing prevention in primary care: are interventions targeted towards consumers’ and providers’ perceived needs? [PDF]

open access: hybrid, 2000
Marie‐Dominique Beaulieu   +3 more
openalex   +1 more source

Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting

open access: yesCirculation, 2017
P. Natarajan   +13 more
semanticscholar   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

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