Results 271 to 280 of about 7,915,710 (337)

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Upscaling effects on infectious disease emergence risk emphasize the need for local planning in primary prevention within biodiversity hotspots. [PDF]

Sci Rep
Muylaert RL, Wilkinson DA, Dwiyanti EI, Hayman DTS.   +3 more
europepmc   +1 more source

Is There a Role of Adding Defibrillation to Cardiac Resynchronization Therapy for Primary Prevention in Patients with Heart Failure and Reduced Ejection Fraction?

Hee Young Lim, Yew Chung Chan, Woon Loong Calvin Chin, Soot Keng   +3 more
openalex   +2 more sources

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

A Quality Improvement Initiative on Documentation of Guideline-Directed Medical Therapy Implementation Among Primary Prevention CRT-D Implant. [PDF]

JACC Case Rep
Wasik S, Moayedi Y, Ha ACT, Nair K, Alba AC, Westcott KV, Chan S, Rubin B, Ross H.   +8 more
europepmc   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Primary prevention implantable cardioverter-defibrillator therapy in non-ischaemic heart failure with reduced left ventricular ejection fraction: a European Heart Rhythm Association survey. [PDF]

Europace
Brociek E, Karvonen J, Mills MT, Ruwald MH, Migliore F, Conte G, Roten L, Futyma P, Marcantoni L, Mazurek M, Sultan A, Duray GZ, Perrotta L, Chun JKR.   +13 more
europepmc   +1 more source

Lipidomic Risk Score to Enhance Cardiovascular Risk Stratification for Primary Prevention

Jing Wu, Corey Giles, Aleksandar Dakic, Habtamu B. Beyene, Kevin Huynh, Tingting Wang, Thomas G. Meikle, Gavriel Olshansky, Agus Salim, Thy Duong, Gerald F. Watts, Joseph Hung, Jennie Hui, Gemma Cadby, John Beilby, John Blangero, Eric K. Moses, Jonathan E. Shaw, Dianna J. Magliano, Dantong Zhu, Jean Yang, Stuart M. Grieve, Andrew Wilson, Clara K Chow, Stephen T. Vernon, Michael P. Gray, Gemma A. Figtree, M. Carrington, Michael Inouye, Thomas H. Marwick, Peter J. Meikle   +30 more
openalex   +1 more source

Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong, Min‐Hee Lee, Hiroshi Uda, Yoon Ho Hwang, Michael Behen, Aimee Luat, Csaba Juhász, Eishi Asano   +7 more
wiley   +1 more source

Amyotrophic Lateral Sclerosis Prevalence Projection in 2040: A Less Rare Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To project ALS prevalence across multiple countries through 2040, accounting for both population aging and increased survival. Methods Data from the Piemonte and Valle d'Aosta ALS register (PARALS) was used to estimate the trends in incidence and prevalence from 2005 to 2019. Survival trends over this period were also assessed.
Rosario Vasta, Stefano Callegaro, Antonio Canosa, Umberto Manera, Maurizio Grassano, Francesca Palumbo, Sara Cabras, Enrico Matteoni, Francesca Di Pede, Filippo De Mattei, Salvatore Tafaro, Neil M. Thakur, Ryan Grosenick, Fabiola De Marchi, Letizia Mazzini, Cristina Moglia, Andrea Calvo, Kuldip D. Dave, Adriano Chiò   +18 more
wiley   +1 more source