Results 101 to 110 of about 5,546,226 (282)

Effects of typhoons on primary production and dissolved oxygen in the East China Sea

Frontiers in Marine Science
Previous investigations confirm that typhoons deliver both dissolved oxygen and nutrient sources via promoting vertical/lateral exchanges between water masses.
Wen Yang, Haokun Wu, Wenxia Zhang, Wenxia Zhang   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Revisit of Plant Food Waste Along Food Supply Chains: Impacts and Perspectives

Foods
More than one billion tons of the food produced in the world ends up being wasted every year, accounting for about one-third of the food produced globally.
Joana Gonçalves, Ofélia Anjos, Raquel P. F. Guiné   +2 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Market-dependent production set [PDF]

A country’s production possibility frontier or PPF is defined as the boundary of its economy’s production set in the net output space for a given technology and fixed quantities of primary factors of production.
Egbert, Henrik, Naqvi, Nadeem
core   +1 more source

A new model of cosmogenic production of radiocarbon 14C in the atmosphere

, 2012
We present the results of full new calculation of radiocarbon 14C production in the Earth atmosphere, using a numerical Monte-Carlo model. We provide, for the first time, a tabulated 14C yield function for the energy of primary cosmic ray particles ...
Adriani, Alanko-Huotari, Alcaraz, Alcaraz, Alexander Mishev, Bard, Beer, Beer, Bolin, Burger, Castagnoli, Clem, Damon, Desorgher, Dorman, Dorman, Elsasser, Garcia-Munoz, Gennady A. Kovaltsov, Goslar, Hedin, Herbst, Hudson, Ilya G. Usoskin, Korff, Korte, Kovaltsov, Kromer, Lal, Lal, LaViolette, Light, Lingenfelter, Lingenfelter, Lockwood, Masarik, Masarik, Masarik, McCracken, Muscheler, Nakamura, O'Brien, O'Brien, O'Brien, O'Brien, Picone, Reimer, Simpson, Snowball, Solanki, Steinhilber, Stuiver, Stuiver, Usoskin, Usoskin, Usoskin, Usoskin, Usoskin, Usoskin, Webber, Webber, Webber   +61 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Surface primary producer phenology in Dease Strait, NU, Canada, examined using submersed oceanographic sensors and satellite remote sensing

Arctic Science
Thinning sea ice cover and earlier melt in the Arctic impact primary producer (PP) phenology, causing earlier ice algal bloom termination and phytoplankton bloom commencement.
Kiran Yendamuri, Julienne Stroeve, Jens K. Ehn, William J. Williams, Vishnu Nandan, Brent G.T. Else, Alexander S. Komarov, Christina A. Braybrook, Mike Dempsey, C.J. Mundy   +9 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source