Results 141 to 150 of about 5,609,357 (351)
Primary Production and Nutrient Dynamics of Urban Ponds
Muriel Rolon dos Santos Mérette
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Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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The phytoplankton and macrophytes are the main primary producers in the ecosystem of Tonle Sap Lake (TSL). The average biomasses of the phytoplankton and macrophytes in TSL were estimated at 5.48 ton/km2 and 1489 ton/km2, with the ratios of production to biomass being 185/year and 1.67/year, respectively.
openaire
Effect of electrolyzed oxidizing water on reducing Campylobacter spp. in broiler chikken at primary production [PDF]
Eva-Maria Bügener +3 more
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Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
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Given the importance of coastal upwelling systems to ocean productivity, fisheries, and biogeochemical cycles, their response to climate change is of great interest.
Michael G. Jacox +8 more
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Effects of anthropogenic activity on global terrestrial gross primary production (LAI and FAPAR)
Irina Melnikova, T. Sasai
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Amplification and attenuation of increased primary production in a marine food web [PDF]
Kelly Kearney +2 more
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