Results 251 to 260 of about 5,609,357 (351)

Smaller and bolder fish enhance ecosystem-scale primary production around artificial reefs in seagrass beds. [PDF]

Ecol Appl
Munsterman KS, Hesselbarth MHK, Allgeier JE.   +2 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Abscisic Acid Accumulation Maintains Maize Primary Root Elongation at Low Water Potentials by Restricting Ethylene Production

, 2000
William G. Spollen, Mary E. LeNoble, Timmy D. Samuels, Nirit Bernstein, Robert E. Sharp   +4 more
openalex   +2 more sources

Nitrogen fixation may not alleviate stoichiometric imbalances that limit primary production in eutrophic lake ecosystems. [PDF]

Ecology
Andersen IM, Taylor JM, Kelly PT, Hoke AK, Robbins CJ, Scott JT.   +5 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Seafloor primary production in a changing Arctic Ocean. [PDF]

Proc Natl Acad Sci U S A
Attard K, Singh RK, Gattuso JP, Filbee-Dexter K, Krause-Jensen D, Kühl M, Sejr MK, Archambault P, Babin M, Bélanger S, Berg P, Glud RN, Hancke K, Jänicke S, Qin J, Rysgaard S, Sørensen EB, Tachon F, Wenzhöfer F, Ardyna M.   +19 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Identifying a growth and survival bottleneck: oceanic zooplankton abundance and Faroe shelf primary production jointly influence the survival of Faroe Plateau cod larvae. [PDF]

J Plankton Res
Jacobsen S, Vang HBM, Eliasen SK, Húsgarð Larsen KM, Gaard E, Grønkjær P, Hátún H.   +6 more
europepmc   +1 more source

Potential primary production of unirrigated land in the Sahel [PDF]

Heemst, H.D.J., van, Penning de Vries, F.W.T.   +1 more
core   +2 more sources

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source