Results 121 to 130 of about 38,398 (233)

Shared genes and pathways in dementia: Insights from genome‐wide association studies

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract Dementia, a collective term for neurodegenerative disorders marked by cognitive decline, affects millions worldwide, and is expected to rise significantly in prevalence. Genome‐wide association studies (GWASs), as highlighted in this review, have revolutionized our understanding of dementia by identifying contributing genetic loci and pathways,
Kyle J. Loi, Noah Radtke, Chloe Kiriluk, Mohamed H. Noureldein, Eva L. Feldman, Kelly M. Bakulski, Kevin S. Chen   +6 more
wiley   +1 more source

POSITIVE IMPACT OF SPEECH THERAPY IN PROGRESSIVE NON-FLUENT APHASIA

Acta Colombiana de Psicología
The aim of this paper is to analyze the effects of intensive speech therapy intervention in a case of progressive non-fluent aphasia (PNFA). This is a dementia syndrome characterized by a progressive deficit in expressive language fluency and syntactic ...
Paola Andrade-Calderón, Judith Salvador-Cruz, Ana Luisa Sosa-Ortiz   +2 more
doaj   +1 more source

Right Hemisphere Involvement in Non-Fluent Primary Progressive Aphasia

Behavioural Neurology, 2007
We described a 56-years-old man with a diagnosis of “non-fluent primary progressive aphasia” (NfPPA). An accurate neuropsychological, neurological and neuroimaging evaluation was performed in order to assess clinical and behavioural features of the ...
Claudia Repetto, Rosa Manenti, Maria Cotelli, Marco Calabria, Orazio Zanetti, Barbara Borroni, Alessandro Padovani, Carlo Miniussi   +7 more
doaj   +1 more source

The Efficacy of Tele-practice on Expressive Language Outcomes for Adults with Aphasia [PDF]

, 2018
Access to skilled speech and language intervention can be difficult for individuals residing in rural areas as well as for individuals with complex health and mobility issues.
Bailey, Morgan, Burningham, Lauren, Fifield, Erin   +2 more
core   +1 more source

Neuropsychiatric symptom phenotypes for early detection of risk in older adults

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION We examined whether early neuropsychiatric symptom (NPS) patterns were associated with cognitive and neuropathologic changes. METHODS Latent class analysis within 20,599 cognitively unimpaired older adults in the National Alzheimer's Coordinating Center dataset identified NPS phenotypes.
Fareshte Erani, Caitlin M. Terao, Shanna Cooper, Alexandra J. Weigand, Katherine J. Bangen, Emily C. Edmonds, David G. Coughlin, Kelsey R. Thomas   +7 more
wiley   +1 more source

Blood‐based Alzheimer's disease biomarkers in a behavioral neurology clinic: Real‐world implementation, clinical utility, and diagnostic performance

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION Blood‐based biomarkers (BBMs) for Alzheimer's disease (AD), including plasma phosphorylated tau (p‐tau), are increasingly used in clinical practice, but “real‐world” implementation patterns, context‐of‐use (COU), clinical utility, and diagnostic performance are incompletely understood. METHODS A retrospective analysis of the first
Igor Prufer Q C Araujo, Tara Ellingson, Nicholas U. Schwartz, Connor D. Dietz, Gautam Tammewar, Kaancan Deniz, Manizhe Eslami‐Amirabadi, Andrew G. Breithaupt, Marci Rosenberg, Nhat Minh Bui, Yasmeen Gonzalez, Renaud La Joie, Peter A. Ljubenkov, Katherine L. Possin, Julio C. Rojas, David N. Soleimani‐Meigooni, Yingbing Wang, Adam M. Staffaroni, Melanie L. Stephens, Elena Tsoy, Charles C. Windon, Adam L. Boxer, Gil D. Rabinovici, Bruce L. Miller, Lawren VandeVrede   +24 more
wiley   +1 more source

Mapping Postictal Aphasia through Signal Complexity: A Stereo‐Electroencephalography Study

Annals of Neurology, Volume 98, Issue 5, Page 1080-1095, November 2025.
Objective The postictal period provides an opportunity to investigate the pathophysiology underlying aphasia and recovery following epileptic seizures. This study examines postictal aphasia in stereo‐electroencephalography (SEEG)‐explored patients to identify brain regions associated with task‐specific language deficits using signal complexity analysis.
Ionuț‐Flavius Bratu, Christian G. Bénar, Samuel Medina Villalon, Lison Ciavatti, Fantine Mazel, Fabrice Bartolomei, Agnès Trébuchon   +6 more
wiley   +1 more source

Logopenic aphasia or Alzheimer's disease: Different phases of the same disease?

Dementia & Neuropsychologia
The logopenic variant of Primary Progressive Aphasia, or logopenic aphasia, is a the most recently described variant of Primary Progressive Aphasia and also the least well defined.
Bárbara Costa Beber, Renata Kochhann, Bruna Matias da Silva, Marcia L. F. Chaves   +3 more
doaj   +1 more source

Primary progressive aphasia: in search of brief cognitive assessments [PDF]

, 2022
Jordi A. Matías‐Guiu, Stephanie M. Grasso   +1 more
openalex   +1 more source

Brain Topology Disruption in Early‐Onset Dementia: Review of Current Findings and the Need for Network Resilience Focused Models

Brain and Behavior, Volume 15, Issue 11, November 2025.
Graphical Abstract This review discusses findings from 23 neuroimaging studies using Electroencephalography (EEG), resting‐state Functional Magnetic Resonance Imaging (rs‐fMRI), Diffusion Tensor Imaging (DTI), and Positron Emission Tomography (PET) to examine brain network topology in Early‐Onset Dementia (EOD), including Frontotemporal Dementia (FTD),
Hema Nawani, Sredha S. Sunil, Ranjith Jaganathan, Veeky Baths   +3 more
wiley   +1 more source