Results 131 to 140 of about 129,162 (296)

The novel MAPT mutation K298E:mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons [PDF]

open access: yes, 2013
Frontotemporal lobar degeneration (FTLD) consists of a group of neurodegenerative diseases characterized by behavioural and executive impairment, language disorders and motor dysfunction.
Calo, Laura   +14 more
core   +4 more sources

A Realist Evaluation of the Implementation and Use of Patient‐Reported Outcomes in Four Value‐Based Healthcare Programmes

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To investigate what works when using Patient‐Reported Outcome Measures (PROMs), for whom, in what contexts, and why in four Value‐Based Healthcare (VBHC) programmes. Design Realist evaluation. Methods Evaluation of Heart Failure, Parkinson's Disease, Epilepsy and Cataract surgery programmes using data from a scoping review, documentary ...
Mayara S. Bianchim   +6 more
wiley   +1 more source

An interdisciplinary approach aiding the diagnosis of primary progressive aphasia: A case report

open access: yesDementia & Neuropsychologia
Frontotemporal dementia (FTD) is one of the most common causes of early-onset dementia with primary progressive aphasia (PPA) being the second-most-frequent form of this degenerative disease.
Nadia Shigaeff   +5 more
doaj   +1 more source

How artificial intelligence is shaping neuropsychology: A focus on cognitive assessment of neurodegenerative disorders

open access: yesJournal of Neuropsychology, EarlyView.
Abstract Artificial intelligence (AI) and machine learning (ML) algorithms are revolutionising the world, and they have the potential to revolutionise neuropsychology as well. A particularly fruitful field for this revolution is the cognitive assessment of neurodegenerative disorders, such as Alzheimer's disease, Parkinson's disease, Mild Cognitive ...
Michele Scandola   +3 more
wiley   +1 more source

Decision Making Cognition in Primary Progressive Aphasia

open access: yesBehavioural Neurology, 2012
We sought to investigate the decision making profile of Primary Progressive Aphasia (PPA) by assessing patients diagnosed with this disease (n = 10), patients diagnosed with behavioral variant frontotemporal dementia (bvFTD, n = 35), and matched controls
Ezequiel Gleichgerrcht   +7 more
doaj   +1 more source

Progressive compromise of nouns and action verbs in posterior cortical atrophy [PDF]

open access: yes, 2018
Processing of nouns and action verbs can be differentially compromised following lesions to posterior and anterior/motor brain regions, respectively. However, little is known about how these deficits progress in the course of neurodegeneration.
Borovinsky, Geraldine   +9 more
core   +1 more source

Category fluency and creative potential in semantic aphasia

open access: yesJournal of Neuropsychology, EarlyView.
Abstract Creative cognition involves linking weakly or unrelated concepts, enabled by semantic control (inhibiting dominant associations to retrieve weaker ones) or through spreading activation within the semantic system. Semantic aphasia (SA) patients have impaired semantic control despite relatively preserved semantic representations.
Hannah E. Thompson   +4 more
wiley   +1 more source

Primary progressive aphasia: clinicopathological correlations [PDF]

open access: yesNature Reviews Neurology, 2010
Primary progressive aphasia (PPA) is a disorder of declining language that is a frequent presentation of neurodegenerative diseases such as frontotemporal lobar degeneration. Three variants of PPA are recognized: progressive nonfluent aphasia, semantic dementia, and logopenic progressive aphasia.
openaire   +2 more sources

The Language Profile of Behavioral Variant Frontotemporal Dementia [PDF]

open access: yes, 2016
BACKGROUND: The language profile of behavioral variant frontotemporal dementia (bvFTD) remains to be fully defined. OBJECTIVE: We aimed to quantify the extent of language deficits in this patient group.
Buckley, AH   +9 more
core   +1 more source

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